Evidence map›Paper›PMID 39739041›Full record

ReviewEuropean radiology2025

Prostate cancer MRI methodological radiomics score: a EuSoMII radiomics auditing group initiative.

Armando Ugo Cavallo, Arnaldo Stanzione, Andrea Ponsiglione, Romina Trotta, Salvatore Claudio Fanni, Samuele Ghezzo, Federica Vernuccio, Michail E Klontzas, Matthaios Triantafyllou, Lorenzo Ugga and 3 more

Abstract readReview
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In one paragraph

Review in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Armando Ugo CavalloIstituto Dermopatico dell'Immacolata (IDI) IRCCS, Rome, Italy.
Arnaldo StanzioneDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Andrea PonsiglioneDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy. andrea.ponsiglione@unina.it.ORCID http://orcid.org/0000-0002-0105-935X
Romina TrottaDepartment of Radiology, Fatima Hospital, Seville, Spain.
Salvatore Claudio FanniDepartment of Translational Research, Academic Radiology, University of Pisa, Pisa, Italy.
Samuele GhezzoVita-Salute San Raffaele University, Milan, Italy.
Federica VernuccioSection of Radiology, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.
Michail E KlontzasArtificial Intelligence and Translational Imaging (ATI) Lab, Department of Radiology, School of Medicine, University of Crete, Heraklion, Greece.
Matthaios TriantafyllouArtificial Intelligence and Translational Imaging (ATI) Lab, Department of Radiology, School of Medicine, University of Crete, Heraklion, Greece.
Lorenzo UggaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Naples, Italy.
Georgios KalarakisDivision of Radiology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Roberto CannellaSection of Radiology, Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), University of Palermo, Palermo, Italy.
Renato CuocoloDepartment of Medicine, Surgery, and Dentistry, University of Salerno, Baronissi, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the quality of radiomics research in prostate MRI for the evaluation of prostate cancer (PCa) through the assessment of METhodological RadiomICs (METRICS) score, a new scoring tool recently introduced with the goal of fostering further improvement in radiomics and machine learning methodology. MATERIALS AND

methodsA literature search was conducted from July 1st, 2019, to November 30th, 2023, to identify original investigations assessing MRI-based radiomics in the setting of PCa. Seven readers with varying expertise underwent a quality assessment using METRICS. Subgroup analyses were performed to assess whether the quality score varied according to papers' categories (diagnosis, staging, prognosis, technical) and quality ratings among these latter.

resultsFrom a total of 1106 records, 185 manuscripts were available. Overall, the average METRICS total score was 52% ± 16%. ANOVA and chi-square tests revealed no statistically significant differences between subgroups. Items with the lowest positive scores were adherence to guidelines/checklists (4.9%), handling of confounding factors (14.1%), external testing (15.1%), and the availability of data (15.7%), code (4.3%), and models (1.6%). Conversely, most studies clearly defined patient selection criteria (86.5%), employed a high-quality reference standard (89.2%), and utilized a well-described (85.9%) and clinically applicable (87%) imaging protocol as a radiomics data source.

conclusionThe quality of MRI-based radiomics research for PCa in recent studies demonstrated good homogeneity and overall moderate quality. KEY POINTS: Question To evaluate the quality of MRI-based radiomics research for PCa, assessed through the METRICS score. Findings The average METRICS total score was 52%, reflecting moderate quality in MRI-based radiomics research for PCa, with no statistically significant differences between subgroups. Clinical relevance Enhancing the quality of radiomics research can improve diagnostic accuracy for PCa, leading to better patient outcomes and more informed clinical decision-making.

Indexed as

Magnetic Resonance ImagingProstatic NeoplasmsHumansMaleRadiomicsMagnetic resonance imagingProstateRadiomicsSystematic review

Identifiers

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.