Evidence map›Paper›PMID 39738955›Full record

ReviewSub-cellular biochemistry2024

Nucleic Acid Packaging in Viruses.

María I Daudén, Mar Pérez-Ruiz, José L Carrascosa, Ana Cuervo

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sub-cellular biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

María I DaudénStructural Biology Programme, Spanish National Cancer Research Centre, (CNIO), Madrid, Spain.
Mar Pérez-RuizFaculty of Health and Medical Sciences, Structural Biology of Molecular Machines Group, Protein Structure and Function Program, Novo Nordisk Foundation Centre for Protein Research, University of Copenhagen, Copenhagen, Denmark.
José L CarrascosaDepartment of Macromolecular Structure, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.
Ana CuervoDepartment of Macromolecular Structure, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. acuervo@cnb.csic.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses shield their genetic information by enclosing the viral nucleic acid inside a protein shell (capsid), in a process known as genome packaging. Viruses follow essentially two main strategies to package their genome: Either they co-assemble their genetic material together with the capsid protein or an empty shell (procapsid) is first assembled and then the genome is pumped inside the capsid by a molecular motor that uses the energy released by ATP hydrolysis. During packaging the viral nucleic acid is highly condensed through a meticulous arrangement in concentric layers inside the capsid. In this chapter we will first give an overview of the different strategies used for genome packaging to discuss later some specific virus models where the structures of the main proteins involved are presented and the biophysics underlying the packaging mechanism are discussed.

Indexed as

Capsid ProteinsCapsidDNA PackagingDNA, ViralGenome, ViralHumansRNA, ViralViral Genome PackagingVirus AssemblyVirusesCapsid ProteinsDNA, ViralRNA, ViralBacteriophageCapsidCryogenic electron microscopyDNAEjectionEncapsidationHelical symmetryIcosahedral symmetryMaturationMolecular motorNucleocapsidPackagingPortalRNAShellTerminaseVirusX-ray diffraction

Identifiers

PMID39738955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.