Evidence map›Paper›PMID 39738944›Full record

ReviewSub-cellular biochemistry2024

The Basic Architecture of Viruses.

José R Castón

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sub-cellular biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The virus lesson: Teaching viral structure and quasi-symmetry in mixed reality.Protein science : a publication of the Protein Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

José R CastónDepartment of Macromolecular Structure, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain. jrcaston@cnb.csic.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses are elegant macromolecular assemblies and constitute a paradigm of the economy of genomic resources; they must use simple general principles to complete their life cycles successfully. Viruses need only one or a few different capsid structural subunits to build an infectious particle, which is possible for two reasons: extensive use of symmetry and built-in conformational flexibility. Although viruses come in many shapes and sizes, two major symmetric assemblies are found: icosahedral and helical. The enormous diversity of virus structures appears to be derived from one or a limited number of basic schemes that became more complex by consecutive incorporation of additional structural elements. The intrinsic structural polymorphism of the viral proteins results in dynamic capsids. The study of virus structures is required to understand structure-function relationships, including those related to morphogenesis and antigenicity, among many others. These structural foundations can be extended to other macromolecular complexes that control many fundamental processes in biology.

Indexed as

CapsidVirusesAnimalsCapsid ProteinsHumansModels, MolecularViral ProteinsVirus AssemblyCapsid ProteinsViral ProteinsCapsidConformational polymorphismHelical symmetryIcosahedral symmetryMetastable capsidMolecular switchNucleocapsidProlate capsidQuasi-equivalenceTriangulation number

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.