Evidence map›Paper›PMID 39738672›Full record

ArticlePediatric cardiology2026

Lower Child Opportunity Index is Associated with Lower Exercise Capacity Post-Fontan Palliation.

Brock A Karolcik, Li Wang, Maya I Ragavan, Arvind K Hoskoppal, Anita P Saraf, Gaurav Arora, Jacqueline Kreutzer, Melita L Viegas, Tarek Alsaied

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brock A KarolcikDivision of Pediatric Cardiology, Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, 5Th Floor Faculty Pavilion, Pittsburgh, PA, 15224, USA. karolcikba@upmc.edu.
Li WangUniversity of Pittsburgh, Clinical and Translational Science Institute, Pittsburgh, PA, USA.
Maya I RagavanDivision of General Academic Pediatrics, Department of Pediatrics, University of Pittsburgh School of Medicine and UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Arvind K HoskoppalDivision of Pediatric Cardiology, Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, 5Th Floor Faculty Pavilion, Pittsburgh, PA, 15224, USA.
Anita P SarafDivision of Pediatric Cardiology, Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, 5Th Floor Faculty Pavilion, Pittsburgh, PA, 15224, USA.
Gaurav AroraDivision of Pediatric Cardiology, Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, 5Th Floor Faculty Pavilion, Pittsburgh, PA, 15224, USA.
Jacqueline KreutzerDivision of Pediatric Cardiology, Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, 5Th Floor Faculty Pavilion, Pittsburgh, PA, 15224, USA.
Melita L ViegasDivision of Pediatric Cardiothoracic Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.
Tarek AlsaiedDivision of Pediatric Cardiology, Department of Pediatrics, University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, 5Th Floor Faculty Pavilion, Pittsburgh, PA, 15224, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Child Opportunity Index (COI) is a validated measurement that uses a composite index of 29 indicators of social determinants of health linked to the US Census. Patients post-Fontan palliation for single ventricle physiology often have reduced exercise capacity compared to the general population. Our hypothesis is that COI levels are directly associated with exercise capacity and inversely with late outcomes. A retrospective, single-center study was performed, including 99 patients post-Fontan procedure who had cardiac magnetic resonance imaging at our institution from January 2010 to July 2023, of which 78 had undergone an exercise test. Univariate analysis was performed with Pearson correlational testing and multivariable linear regression was then used to evaluate independent predictors of % predicted VO

Indexed as

Exercise ToleranceFontan ProcedureHeart Defects, CongenitalSocial Determinants of HealthAdolescentAdultChildExercise TestFemaleHumansMaleRetrospective StudiesYoung AdultAdult congenital heart diseaseChild opportunity indexExercise capacityFontanSocial determinants of Health

Identifiers

PMID39738672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.