Evidence map›Paper›PMID 39738526›Full record

ArticleScientific reports2024

Epidemiology and diversity of Plasmodium species in Franceville and their implications for malaria control.

Larson Boundenga, Yann Vital Sima-Biyang, Neil Michel Longo-Pendy, Michelle Bignoumba, Clark Mbou-Boutambe, Clauve Jauvert Moukagni-Mussadji, Dorothé Marielle Wora, Fabrice Kassa-Kassa, Richard Onanga, Cyrille Bisseye and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Larson BoundengaInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon. boundenga@gmail.com.
Yann Vital Sima-BiyangInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Neil Michel Longo-PendyInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Michelle BignoumbaInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Clark Mbou-BoutambeInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Clauve Jauvert Moukagni-MussadjiInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Dorothé Marielle WoraInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Fabrice Kassa-KassaInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Richard OnangaInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.
Cyrille BisseyeCellular Biology (LABMC), Masuku University of Science and Technology, Franceville, Gabon.
Francine NtoumiFondation Congolaise pour la Recherche Medicale (FCRM), Brazzaville, Republic of the Congo.
Ayola Akim AdegnikaInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Jean-Bernard Lekana-DoukiInterdisciplinary Centre of Medical Research of Franceville (CIRMF), Franceville, Gabon.

Funding

EDCTP 1045 CANTAM2 EDCTP ReNet2015
6 · The paper itself

Abstract

Malaria is a significant public health challenge in Gabon, with high prevalence rates in rural and semi-urban areas. This study investigated Plasmodium infection prevalence among outpatients at a medical laboratory in Franceville, Gabon, in 2020. Data from 500 patients were analyzed, revealing an overall infection rate of 33.2% and the presence of four Plasmodium species: P. falciparum, P. malariae, P. ovale, and possibly P. vivax for the first time in Gabon. Co-infections were common, with P. falciparum and P. ovale spp. being the most prevalent at 23.5%. Asymptomatic infections accounted for 81.3% of cases, while symptomatic infections were 18.7%. P. falciparum was associated with symptomatic cases, while non-falciparum species were linked to asymptomatic infections. The findings suggest Franceville has perennial malaria transmission, highlighting the role of Plasmodium species diversity in disease severity and clinical presentation, including the first report of P. vivax infection in the Gabonese population.

Indexed as

MalariaPlasmodiumAdolescentAdultAgedChildChild, PreschoolCoinfectionFemaleGabonHumansInfantMaleMiddle AgedPlasmodium ovalePlasmodium vivaxDiagnosisFrancevilleGabonMalariaPlasmodium species

Identifiers

PMID39738526
PMCPMC11686293

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.