Evidence map›Paper›PMID 39738507›Full record

ArticleScientific reports2024

The natural herbicide rhein targets photosystem I.

Alyssa Twitty, Hamlin Barnes, Noa Levy, Yaniv Mizrahi, Yosef Geva, Yael Phillip, Franck E Dayan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alyssa TwittyDepartment of Agricultural Biology, Colorado State University, Fort Collins, CO, USA.ORCID 0009-0004-8862-6290
Hamlin BarnesDepartment of Agricultural Biology, Colorado State University, Fort Collins, CO, USA.ORCID 0009-0002-7884-3051
Noa LevyAgrematch Ltd., 10 Prof. Menahem Plaut St., Rehovot Science Park, Rehovot, Israel.ORCID 0009-0000-2078-4277
Yaniv MizrahiAgrematch Ltd., 10 Prof. Menahem Plaut St., Rehovot Science Park, Rehovot, Israel.ORCID 0009-0006-4572-6368
Yosef GevaAgrematch Ltd., 10 Prof. Menahem Plaut St., Rehovot Science Park, Rehovot, Israel.ORCID 0000-0002-4652-7049
Yael PhillipAgrematch Ltd., 10 Prof. Menahem Plaut St., Rehovot Science Park, Rehovot, Israel.ORCID 0000-0001-6619-1119
Franck E DayanDepartment of Agricultural Biology, Colorado State University, Fort Collins, CO, USA. franck.dayan@colostate.edu.ORCID 0000-0001-6964-2499

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The natural anthraquinone rhein has been identified as a novel herbicide with a potentially new mode of action using a generative AI system for functional molecules discovery. Its herbicidal activity was light-dependent and resulted in rapid burndown symptoms on leaves of treated plants. Rhein interferes with photosynthesis by acting as an electron diverter at the level of photosystem I (PSI). The redox potential of rhein suggests that it accepts electrons between P700 and NADP

Indexed as

AnthraquinonesHerbicidesOxidation-ReductionPhotosystem I Protein ComplexElectron TransportLightPhotosynthesisPlant LeavesReactive Oxygen SpeciesAnthraquinonesHerbicidesPhotosystem I Protein ComplexReactive Oxygen SpeciesrheinAIAnthraquinoneArtificial intelligenceElectron acceptorFlavoproteinGenerative AILight-dependentMode of actionNatural productPhotosystem IROS

Identifiers

PMID39738507
PMCPMC11685900

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.