ArticleScientific reports2024
Global burden and trends of testicular cancer in adolescents and young adults from 1990 to 2021, with predictions to 2035.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Stigma experiences among young and middle-aged testicular cancer survivors in China: A phenomenological study.Asia-Pacific journal of oncology nursing · 2026Article
- Adolescents and young adults with cancers: comparative analyses of incidence and survival between Europe and the United States.ESMO real world data and digital oncology · 2026Article
- Circulating Tumor Function: A Systems Biology Framework for Liquid Biopsy in Genitourinary Cancers.Genes · 2026Review
- Multiparametric Ultrasound for Characterisation of Testicular Lesions: Beyond Orchiectomy.Diagnostics (Basel, Switzerland) · 2026Review
- A Retrospective Analysis of Testicular Cancer (2007-2025): A Single Institutional Experience.Research and reports in urology · 2026Article
- Trends and projections of global testicular cancer burden from 1990 to 2035.Frontiers in oncology · 2026Article
- Liquid biopsy in genitourinary cancers: Diagnostic and prognostic implications.World journal of clinical oncology · 2025Review
- Tracking and analysis of testicular cancer burden in adolescents and young adults globally in Asia and in China: 1990-2021 epidemiological trends.Translational andrology and urology · 2025Article
- Disease burden of bladder cancer in China and the different SDI regions over the world from 1990 to 2021.Scientific reports · 2025Article
- Global, regional, and national epidemiology of ischemic stroke in young adults, 1990-2021.Journal of neurology · 2025Article
- Article
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Abstract
Testicular cancer predominantly affects adolescents and young adults (AYAs) aged 15-39 years. This study analyzed the global, regional, and national burden of testicular cancer among AYAs (1990 to 2021). Data from the Global Burden of Disease study was used to calculate age-standardized rates of incidence (ASIR), prevalence (ASPR), and disability-adjusted life years (ASDR). Trends were assessed using the Joinpoint regression and Bayesian age-period-cohort models, with projections up to 2035. Results showed the global ASIR of 4.05 (95% CI: 3.80-4.35), ASPR of 31.05 (95% CI: 28.88-33.68), and ASDR of 24.82 (95% CI: 22.99-26.91) per 100,000 in 2021, respectively. From 1990 to 2021, ASIR and ASPR increased, while ASDR remained relatively stable. Significant geographical disparities were observed, with Europe and Latin America showing higher burdens compared to Asia and Africa. The 25-29 age group had the highest age-specific rate of incidence (5.58; 95% UI: 5.25-5.97) and disability-adjusted life years (34.09; 95% UI: 31.55-37.11) per 100,000, while the 30-34 age group had the highest age-specific prevalence rate (43.12; 95% UI: 40.51-46.56) per 100,000 in 2021. By 2035, the global numbers of incidence and prevalence cases were projected to increase, with DALYs and age-standardized rates declining. These findings are crucial for informing global strategies in testicular cancer prevention.
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