Evidence map›Paper›PMID 39738358›Full record

ArticleScientific reports2024

Association between allergen-specific immunoglobulin E sensitization, allergic rhinitis symptoms, and quality of life in school-aged children.

Daisuke Watanabe, Sanae Otawa, Megumi Kushima, Hideki Yui, Ryoji Shinohara, Zentaro Yamagata, Daiju Sakurai, Kunio Miyake, Yamanashi Adjunct Study of the Japan Environment and Children’s Study Group

Abstract read
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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daisuke WatanabeDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan.
Sanae OtawaCenter for Birth Cohort Studies, University of Yamanashi, Yamanashi, Japan.
Megumi KushimaCenter for Birth Cohort Studies, University of Yamanashi, Yamanashi, Japan.
Hideki YuiCenter for Birth Cohort Studies, University of Yamanashi, Yamanashi, Japan.
Ryoji ShinoharaCenter for Birth Cohort Studies, University of Yamanashi, Yamanashi, Japan.
Zentaro YamagataCenter for Birth Cohort Studies, University of Yamanashi, Yamanashi, Japan.
Daiju SakuraiDepartment of Otorhinolaryngology, Head and Neck Surgery, Faculty of Medicine, Graduate Faculty of Interdisciplinary Research, University of Yamanashi, Yamanashi, Japan.
Kunio MiyakeDepartment of Epidemiology and Environmental Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 1110 Shimokato, Chuo, Yamanashi, 409-3898, Japan. kmiyake@yamanashi.ac.jp.
Yamanashi Adjunct Study of the Japan Environment and Children’s Study Group

Funding

Japanese Ministry of Education, Culture, Sports, Science, and Technology 20H03928TERUMO LIFE SCIENCE FOUNDATION 23-III5024
6 · The paper itself

Abstract

This study aimed to investigate the relationship between allergen-specific immunoglobulin E (IgE) sensitization and allergic rhinitis (AR) symptoms in school-aged children in Japan and to understand the current severity of AR symptoms and the quality of life (QOL) among children with AR. We analyzed data from 8-year-old children who participated in the Yamanashi Adjunct Study of the Japan Environment and Children's Study, focusing on those with complete information on specific IgE levels and AR (1229 for perennial AR [PAR] and 1196 for seasonal AR [SAR]). Sensitization was determined when allergen-specific IgE levels were class 2 (0.70 U/mL) or higher. A total of 656 children (53.4%) were identified as sensitized to house dust mite-specific IgE, comprising 362 (60.6%) boys and 294 (46.5%) girls. For Japanese cedar pollen (JCP)-specific IgE, 820 (68.6%) children were sensitized, with 430 (73.1%) boys and 390 (64.1%) girls. Among children with AR, 40.2% of those with PAR and 78.4% of those with SAR experienced moderate to severe nasal symptoms. This study highlighted the high prevalence of JCP-specific IgE sensitization among school-aged children in Japan and provided insights into the severity of AR symptoms and the impact on QOL in these children.

Indexed as

AllergensImmunoglobulin EQuality of LifeRhinitis, AllergicAnimalsChildCryptomeriaFemaleHumansJapanMalePollenPyroglyphidaeAllergensImmunoglobulin EAllergic rhinitisQuality of lifeSchool-aged childrenSeasonal allergic rhinitis (SAR)SeveritySpecific IgE antibodies

Identifiers

PMID39738358
PMCPMC11686096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.