Evidence map›Paper›PMID 39738284›Full record

ArticleScientific reports2024

A sterilization method for human decellularized vaginal matrices.

Jayson Sueters, Leonie de Boer, Freek Groenman, Judith A F Huirne, Theo H Smit, Sebastian A J Zaat

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jayson SuetersDepartment of Gynaecology, Amsterdam UMC - Location VUmc, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. j.sueters@amsterdamumc.nl.
Leonie de BoerDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC - Location AMC, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Freek GroenmanDepartment of Obstetrics and Gynecology, Amsterdam Reproduction and Development, Amsterdam UMC - Location VUmc, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Judith A F HuirneDepartment of Gynaecology, Amsterdam UMC - Location VUmc, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Theo H SmitDepartment of Gynaecology, Amsterdam UMC - Location VUmc, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Sebastian A J ZaatDepartment of Medical Microbiology and Infection Prevention, Amsterdam UMC - Location AMC, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaginal reconstruction is necessary for various congenital and acquired conditions, including vaginal aplasia, trauma, tumors, and gender incongruency. Current surgical and non-surgical treatments often result in significant complications. Decellularized vaginal matrices (DVMs) from human tissue offer a promising alternative, but require effective sterilization to ensure safety and functionality. This study aimed to develop a sterilization method for decellularized human vaginal wall scaffolds. Based on our previously implemented decellularization technique with minor modifications, we designed and examined three sterilization methods consisting of (i) chemical decellularization, (ii) decellularization with additional peracetic acid/hydrogen peroxide (PAA/H

Indexed as

SterilizationVaginaAnti-Bacterial AgentsDecellularized Extracellular MatrixExtracellular MatrixFemaleHumansHydrogen PeroxidePeracetic AcidTissue ScaffoldsAnti-Bacterial AgentsDecellularized Extracellular MatrixHydrogen PeroxidePeracetic AcidDecellularizationHuman acellular matrixSterilization methodVagina

Identifiers

PMID39738284
PMCPMC11685901

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.