Evidence map›Paper›PMID 39738186›Full record

ArticleScientific reports2024

Rapid optical determination of salivary cortisol responses in individuals undergoing physiological and psychological stress.

Tashfia Ahmed, Michael B Powner, Meha Qassem, Panayiotis A Kyriacou

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tashfia AhmedResearch Centre for Biomedical Engineering (RCBE), School of Science and Technology, City, University of London, Northampton Square, London, EC1V 0HB, UK. tashfia.n.ahmed@gmail.com.ORCID 0000-0001-5760-1964
Michael B PownerCentre for Applied Vision Research, School of Health and Psychological Sciences, City, University of London, Northampton Square, London, EC1V 0HB, UK.ORCID 0000-0003-4913-1004
Meha QassemResearch Centre for Biomedical Engineering (RCBE), School of Science and Technology, City, University of London, Northampton Square, London, EC1V 0HB, UK.
Panayiotis A KyriacouResearch Centre for Biomedical Engineering (RCBE), School of Science and Technology, City, University of London, Northampton Square, London, EC1V 0HB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional methods for management of mental illnesses in the post-pandemic setting can be inaccessible for many individuals due to a multitude of reasons, including financial stresses and anxieties surrounding face-to-face interventions. The use of a point-of-care tool for self-management of stress levels and mental health status is the natural trajectory towards creating solutions for one of the primary contributors to the global burden of disease. Notably, cortisol is the main stress hormone and a key logical indicator of hypothalamic-pituitary adrenal (HPA) axis activity that governs the activation of the human stress system. Therefore, the measurement of cortisol is imperative to lead the discussion of the relationship between psychological stress and mental health deterioration. The aim of the current study was to determine salivary cortisol concentrations of healthy individuals undergoing the MAST protocol for human stress activation, through optical-colorimetric techniques. The study demonstrates the use of the blue tetrazolium (BT) method as successful means of rapid measurement of cortisol in saliva, comparable to the gold-standard technique i.e., enzyme-linked immunoassays (ELISA) with a coefficient of determination (R

Indexed as

HydrocortisoneSalivaStress, PsychologicalAdultColorimetryEnzyme-Linked Immunosorbent AssayFemaleHumansHypothalamo-Hypophyseal SystemMalePituitary-Adrenal SystemStress, PhysiologicalYoung AdultHydrocortisone

Identifiers

PMID39738186
PMCPMC11685491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.