Evidence map›Paper›PMID 39738149›Full record

ArticleScientific reports2024

Effect of selective dorsal rhizotomy on bladder dysfunction in children with spastic cerebral palsy.

Wenbin Jiang, Junlu Wang, Pierre A Robe, Min Wei, Sen Li, Rui Wang, Qijia Zhan, Bo Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wenbin Jiang *Department of Neurosurgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355, Luding Rd., Putuo District, Shanghai, China.
Junlu Wang *Department of Neurosurgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355, Luding Rd., Putuo District, Shanghai, China.
Pierre A RobeDepartment of Neurology and Neurosurgery, University Medical Center of Utrecht, Utrecht, The Netherlands.
Min WeiDepartment of Neurosurgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355, Luding Rd., Putuo District, Shanghai, China.
Sen LiDepartment of Neurosurgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355, Luding Rd., Putuo District, Shanghai, China.
Rui WangDepartment of Neurosurgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355, Luding Rd., Putuo District, Shanghai, China.
Qijia ZhanDepartment of Neurosurgery, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, No. 355, Luding Rd., Putuo District, Shanghai, China. hanbing_1125@163.com.
Bo XiaoDepartment of Neurosurgery, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, No.1678, Dongfang Road, Pudong District, Shanghai, China. xiao977@hotmail.com.

Funding

Science and Technology Commission of Shanghai Municipality 20Y11905800Shanghai Children's Hospital 2020YGZQ05Shanghai Jiao Tong University YG2021QN117
6 · The paper itself

Abstract

This study investigated the prevalence and severity of lower urinary tract symptoms (LUTS) in children with spastic cerebral palsy (SCP) and evaluated the effect of selective dorsal rhizotomy (SDR) in alleviating these symptoms. The study also explored the correlation between postoperative LUTS improvement and intraoperative electrophysiological findings. Prospective data were collected from a consecutive cohort of 247 children with SCP who underwent SDR and were retrospectively analyzed. Pre- and post-operative assessments included muscle tone, motor function, LUTS and intraoperative electrophysiology data were analyzed. Preoperatively, 94 patients (38.1%) had LUTS, and the severity of LUTS negatively correlated with motor function (R=-0.32, P < 0.0001). After SDR, muscle tone decreased, motor function improved (P < 0.0001), and LUTS resolved in 49/94 patients (52.1%). LUTS improvement correlated with a higher proportion of sensory nerves evoking anal sphincter EMG > 20µV. SDR effectively reduces spasticity, improves motor function, and alleviates LUTS in most children with SCP. Intraoperative neurophysiology may predict improvements, warranting further research.

Indexed as

Cerebral PalsyRhizotomyAdolescentChildChild, PreschoolElectromyographyFemaleHumansLower Urinary Tract SymptomsMaleMuscle SpasticityProspective StudiesRetrospective StudiesTreatment OutcomeUrinary BladderBladder dysfunctionIntraoperative neurophysiological monitoringLower urinary tract symptomsSelective dorsal rhizotomySpastic cerebral palsy

Identifiers

PMID39738149
PMCPMC11685953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.