ArticleNature communications2024
Mechanisms of recalcitrant fucoidan breakdown in marine Planctomycetota.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Fucoidans: a new frontier in brown seaweed research and biotechnology.Cell surface (Amsterdam, Netherlands) · 2026Review
- Article
- Synergistic degradation of fucoidans in the ocean.Nature · 2026Article
- Multi-omics and cultivation reveal laminarin-degrading PVC bacteria in the deep sea.Nature communications · 2026Article
- Polysaccharide-Based Approaches for Inflammation Treatment: Anti-Inflammatory Mechanisms, Delivery Approaches and Translational Prospects.Biomolecules · 2026Review
- Two novel strains isolated from a brackish lake constitute Aeoliella fuhlenseeensis sp. nov. and Bythopirellula superficialaquae sp. nov. in the family Lacipirellulaceae.Scientific reports · 2026Article
- Microencapsulation alters pyraclostrobin degradation and reshapes soil microbial communities compared to conventional formulations.Journal of advanced research · 2026Article
- Characterisation of Kothea flammea gen. nov., sp. nov., a planctomycete of the family Pirellulaceae isolated from Fjord Schlei in the Baltic Sea.Scientific reports · 2026Article
- Article
- Four novel Planctomicrobium species isolated from sewage sludge or leakage water of a compost heap in Northern Germany.Scientific reports · 2026Article
- Comparative genomics reveals the molecular basis for divergent algicidal strategies in twoApplied and environmental microbiology · 2026Article
- Seaweed sulfated polysaccharides regulate the gut microbiota-mucosal barrier-innate immunity axis: structural heterogeneity, immunological evidence, and translational prospects.Frontiers in immunology · 2026Review
- The Discovery of Endo-Fucanases in the GH141 Family: A Novel Functional Activity Within the Family.International journal of molecular sciences · 2025Article
- The novel taxon Lacunimicrobium album gen. nov., sp. nov. is constituted by three planctomycetotal strains isolated from freshwater habitats in Northern Germany.Scientific reports · 2025Article
- Tundrisphaera macrotermitis sp. nov., a novel member of the family Isosphaeraceae isolated from the gut of a fungus-growing termite.Scientific reports · 2025Article
- Structural insights into a fucosidase involved in fucoidan degradation.Acta crystallographica. Section F, Structural biology communications · 2025Article
- Structure-function relationship of the GH168 fucanase reveals an unusual enzyme recognition mechanism for sulfated polysaccharide.Nature communications · 2025Article
- Phenotypic and omics analyses of the SordariomycetesmSystems · 2025Article
- Substrate utilization and secondary metabolite biosynthesis in the phylum Planctomycetota.Applied microbiology and biotechnology · 2025Review
- Seasonal and developmental stage changes in mucilage carbohydrate content shape the kelp microbiome.ISME communications · 2025Article
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18 authors.
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Abstract
Marine brown algae produce the highly recalcitrant polysaccharide fucoidan, contributing to long-term oceanic carbon storage and climate regulation. Fucoidan is degraded by specialized heterotrophic bacteria, which promote ecosystem function and global carbon turnover using largely uncharacterized mechanisms. Here, we isolate and study two Planctomycetota strains from the microbiome associated with the alga Fucus spiralis, which grow efficiently on chemically diverse fucoidans. One of the strains appears to internalize the polymer, while the other strain degrades it extracellularly. Multi-omic approaches show that fucoidan breakdown is mediated by the expression of divergent polysaccharide utilization loci, and endo-fucanases of family GH168 are strongly upregulated during fucoidan digestion. Enzymatic assays and structural biology studies reveal how GH168 endo-fucanases degrade various fucoidan cores from brown algae, assisted by auxiliary hydrolytic enzymes. Overall, our results provide insights into fucoidan processing mechanisms in macroalgal-associated bacteria.
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