Evidence map›Paper›PMID 39737969›Full record

ArticleNature communications2024

Differential effects of fine particulate matter constituents on acute coronary syndrome onset.

Yixuan Jiang, Chuyuan Du, Renjie Chen, Jialu Hu, Xinlei Zhu, Xiaowei Xue, Qinglin He, Jun Lu, Junbo Ge, Yong Huo and 1 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Cord blood DNA methylation as a potential mediator in the association between prenatal ambient air pollution and early infant allergic symptoms in a Shanghai birth cohort.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  2. Article
  3. PMEnvironment & health (Washington, D.C.) · 2026
    Article
  4. Article
  5. Differential impacts of short-term PMScience China. Life sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. PMEnvironment & health (Washington, D.C.) · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yixuan Jiang *School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Chuyuan Du *School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Renjie Chen *School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.ORCID 0000-0002-9448-0820
Jialu HuDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China.
Xinlei ZhuSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Xiaowei XueSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Qinglin HeSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Jun LuSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China.
Junbo GeDepartment of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases, Shanghai, China. ge.junbo@zs-hospital.sh.cn.ORCID 0000-0001-9640-8171
Yong HuoDepartment of Cardiology, Peking University First Hospital, Beijing, China. huoyong@263.net.cn.
Haidong KanSchool of Public Health, Key Lab of Public Health Safety of the Ministry of Education, Fudan University, Shanghai, China. kanh@fudan.edu.cn.ORCID 0000-0002-1871-8999

Funding

National Natural Science Foundation of China (National Science Foundation of China) 92043301
6 · The paper itself

Abstract

Fine particulate matter has been linked with acute coronary syndrome. Nevertheless, the key constituents remain unclear. Here, we conduct a nationwide case-crossover study in China during 2015-2021 to quantify the associations between fine particulate matter constituents (organic matter, black carbon, nitrate, sulfate, and ammonium) and acute coronary syndrome, and to identify the critical contributors. Our findings reveal all five constituents are significantly associated with acute coronary syndrome onset. The magnitude of associations peaks on the concurrent day, attenuates thereafter, and becomes null at lag 2 day. The largest effects are observed for organic matter and black carbon, with each interquartile range increase in their concentrations corresponding to 2.15% and 2.03% increases in acute coronary syndrome onset, respectively. These two components also contribute most to the joint effects, accounting for 31% and 22%, respectively. Our findings highlight tailored clinical management and targeted control of carbonaceous components to protect cardiovascular health.

Indexed as

Acute Coronary SyndromeCross-Over StudiesParticulate MatterAgedAir PollutantsChinaFemaleHumansMaleMiddle AgedNitratesSootSulfatesAir PollutantsNitratesParticulate MatterSootSulfates

Identifiers

PMID39737969
PMCPMC11686129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.