Evidence map›Paper›PMID 39737538›Full record

ArticleActa obstetricia et gynecologica Scandinavica2025

Psychological evaluation of candidates for the uterus transplantation French trial.

Léa Karpel, Margaux Nicaise, Marie Carbonnel, Mathilde Le Marchand, Catherine Racowsky, Paul Pirtea, Jean-Marc Ayoubi

Abstract read
In one paragraph

Article in Acta obstetricia et gynecologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. A decade of human uterus transplantation.Acta obstetricia et gynecologica Scandinavica · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Léa KarpelDepartment of Obstetrics, Gynecology and Reproductive Medicine, Foch Hospital, Suresnes, France.
Margaux NicaiseDepartment of Psychopathology, University of Paris, Paris, France.ORCID 0009-0003-5168-238X
Marie CarbonnelDepartment of Obstetrics, Gynecology and Reproductive Medicine, Foch Hospital, Suresnes, France.ORCID 0000-0001-9935-1203
Mathilde Le MarchandDepartment of Clinical Research, Foch Hospital, Suresnes, France.
Catherine RacowskyDepartment of Obstetrics, Gynecology and Reproductive Medicine, Foch Hospital, Suresnes, France.
Paul PirteaDepartment of Obstetrics, Gynecology and Reproductive Medicine, Foch Hospital, Suresnes, France.
Jean-Marc AyoubiDepartment of Obstetrics, Gynecology and Reproductive Medicine, Foch Hospital, Suresnes, France.

Funding

Foch foundationUniversity of Versailles Saint-Quentin-en-Yvelines transplantation chair
6 · The paper itself

Abstract

introductionSince 2017, women with absolute uterine infertility due to Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome have been eligible to participate in a uterine transplantation clinical trial conducted by Foch Hospital in France. The aim of this study is to assess the psychological state of potential candidates, including recipients, their partners, and their living-related donors. MATERIAL AND

methodsSixteen potential uterus transplant candidates, including recipients, partners, and living-related donors, participated in the study. The psychological evaluation of these candidates was conducted using three validated questionnaires: the Dyadic Adjustment Scale (DAS-16), the Hospital Anxiety and Depression Scale (HADS), and the Fertility Quality of Life (FertiQoL) questionnaire.

resultsNo depression symptoms were observed in any participant according to the HADS. Most recipients did not exhibit signs of anxiety; however, three partners and three donors reported moderate to high anxiety levels. A positive correlation was found between the recipient's psychological distress related to infertility (FertiQoL) and the anxiety scores of their donors. The emotional aspect of infertility was identified as the most distressing factor for the recipients.

conclusionsWhile the overall psychological state of the participants was generally good, anxiety was notably present among donors and partners. Therefore, providing psychological support throughout the uterine transplantation process is essential for not only the recipients but also their partners and donors.

Indexed as

46, XX Disorders of Sex DevelopmentCongenital AbnormalitiesInfertility, FemaleMullerian DuctsUterusAdultAnxietyFemaleFranceHumansLiving DonorsQuality of LifeSurveys and Questionnairesanxietyassessment scalesinfertilitypsychologyquality of lifeuterine transplantation

Identifiers

PMID39737538
PMCPMC11871084

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.