Evidence map›Paper›PMID 39737468›Full record

ArticleBrain communications2025

Increased cell-free DNA in CSF and serum of hip fracture patients with delirium.

Vibeke Bratseth, Leiv Otto Watne, Bjørn Erik Neerland, Nathalie Bodd Halaas, Christian Thomas Pollmann, Adi Karabeg, Olav Tobias Odegaard, Kristian Sydnes, Henrik Zetterberg, Ingebjørg Seljeflot and 1 more

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Vibeke BratsethOslo Center for Clinical Heart Research, Department of Cardiology Ullevaal, Oslo University Hospital, Oslo 0424, Norway.ORCID https://orcid.org/0000-0003-2775-4219
Leiv Otto WatneOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, Oslo 0424, Norway.
Bjørn Erik NeerlandOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, Oslo 0424, Norway.
Nathalie Bodd HalaasOslo Delirium Research Group, Department of Geriatric Medicine, Oslo University Hospital, Oslo 0424, Norway.
Christian Thomas PollmannDepartment of Orthopedic Surgery, Akershus University Hospital, Lørenskog 1478, Norway.
Adi KarabegDepartment of Orthopedic Surgery, Akershus University Hospital, Kongsvinger 2381, Norway.
Olav Tobias OdegaardDepartment of Anesthesiology, Akershus University Hospital, Kongsvinger 2381, Norway.
Kristian SydnesDepartment of Orthopedic Surgery, Diakonhjemmet Hospital, Oslo 0319, Norway.
Henrik ZetterbergInstitute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Mölndal 40530, Sweden.ORCID https://orcid.org/0000-0003-3930-4354
Ingebjørg SeljeflotOslo Center for Clinical Heart Research, Department of Cardiology Ullevaal, Oslo University Hospital, Oslo 0424, Norway.ORCID https://orcid.org/0000-0003-4071-3358
Ragnhild HelsethOslo Center for Clinical Heart Research, Department of Cardiology Ullevaal, Oslo University Hospital, Oslo 0424, Norway.

Funding

Wellcome Trust
6 · The paper itself

Abstract

Delirium is a neuropsychiatric syndrome commonly presenting during acute illness. The pathophysiology of delirium is unknown, but neuroinflammation is suggested to play a role. In this cross-sectional study, we aimed to investigate whether cell-free DNA and markers of neutrophil extracellular traps in serum and CSF were associated with delirium and neuronal damage, assessed by neurofilament light chain. Hip fracture patients (

Indexed as

cell-free DNAdeliriumneurofilament light chainneuroinflammationneutrophil extracellular traps

Identifiers

PMID39737468
PMCPMC11683831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.