ArticleCureus2024
Rectal Administration of Propylthiouracil in a Critically Ill Patient: A Life-Saving Experience.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Hyperthyroidism is a common endocrine disease caused by the production of thyroid hormones in excessive amounts. Propylthiouracil (PTU) is one of the anti-thyroid drugs (ATD) used in the treatment of hyperthyroidism. Rectal PTU should be considered by physicians as a valuable option for managing hyperthyroidism as an alternative route of administration for patients who cannot tolerate oral medications. Our patient presented to the emergency department with acute abdomen. At the same time, he had thyroid storm which required the administration of oral PTU with other medications; however, post surgery, he was kept nil by mouth. Here, we highlight a case of the life-saving administration of rectal administration of propylthiouracil in a patient with a perforated gastric ulcer.
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