ArticleCureus2024
Erdheim-Chester Disease: A Case Report Exploring Multisystemic Involvement.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Incidental Diagnosis of Erdheim-Chester Disease in a 42-Year-Old Man With Persistent Elevated ESR and Peri-Ocular Xanthomas: A Case Report.Clinical case reports · 2026Article
- [A circuitous route to the diagnosis of a very rare disease].Innere Medizin (Heidelberg, Germany) · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Erdheim-Chester disease (ECD) is a rare, multisystemic, non-Langerhans cell histiocytic neoplasm predominantly affecting middle-aged males in their fifth to seventh decades of life. It often presents with nonspecific symptoms, leading to a delay in its diagnosis. We report a case of an 85-year-old male with multisystemic manifestations, including retroperitoneal, skeletal, vascular, cardiac, orbital, and central nervous system (CNS) involvement. Imaging revealed characteristic findings such as bilateral osteosclerosis, perirenal infiltration (hairy kidney sign), and dural-based intracranial masses. Histopathological analysis confirmed the diagnosis, identifying CD68+ histiocytes and the BRAFV600E mutation. The patient was managed initially by Internal Medicine and later referred to Hemato-Oncology for further treatment. This report highlights the importance of maintaining a high index of suspicion for this rare disorder, as well as adopting a multidisciplinary approach toward its treatment, integrating clinical, radiological, and histopathological data.
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Registered trials
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