Evidence map›Paper›PMID 39737092›Full record

ArticleNeuro-oncology advances

Evaluation of early metabolic changes following vorasidenib using FET PET in patients with

Norbert Galldiks, Jan-Michael Werner, Isabelle Stetter, Hannah C Puhr, Thomas S Nakuz, Gabriele Stoffels, Nathalie L Albert, Karl-Josef Langen, Philipp Lohmann, Matthias Preusser

Registry-linked trialAbstract read
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07469735 (18F-AGX PET for Evaluation of Vorasidenib Response and Tumor Metabolic Changes in Low-grade IDH-Mutant Glioma), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07469735 nanot yet recruitingnot on this map

18F-AGX PET for Evaluation of Vorasidenib Response and Tumor Metabolic Changes in Low-grade IDH-Mutant Glioma

TypeinterventionalSponsorHuashan HospitalRan2026 to 2027Enrolled10ConditionsGlioma, Diffuse Glioma, Recurrent GliomasArmsOral Vorasidenib administered once daily for up to 12 treatment cycles (28 days per cycle) as IDH-targeted therapy in participants with recurrent or residual IDH-mutant diffuse glioma.
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Accelerating discovery: Transformative clinical trial models in neuro-oncology.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Norbert GalldiksCenter of Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Cologne, Germany.ORCID https://orcid.org/0000-0002-2485-1796
Jan-Michael WernerDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0001-7147-4594
Isabelle StetterDepartment of Neurology, Faculty of Medicine and University Hospital Cologne, Cologne, Germany.
Hannah C PuhrDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Thomas S NakuzDivision of Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Gabriele StoffelsInstitute of Neuroscience and Medicine (INM-3, INM-4), Research Center Juelich, Juelich, Germany.ORCID https://orcid.org/0000-0001-7114-1941
Nathalie L AlbertDepartment of Nuclear Medicine, LMU University Hospital, Munich, Germany.
Karl-Josef LangenDepartment of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.
Philipp LohmannDepartment of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.ORCID https://orcid.org/0000-0002-5360-046X
Matthias PreusserDivision of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phase-3 INDIGO trial demonstrated that the isocitrate dehydrogenase (

Identifiers

PMID39737092
PMCPMC11683584

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.