ArticleOpen veterinary journal2024
Clinical and molecular identification of Newcastle disease virus in naturally infected chicks in Thi-Qar province of Iraq.
Article in Open veterinary journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The impact of innate and humoral immune mechanisms on vaccine induced protection against avian influenza H9N2 in broilers.Scientific reports · 2025Article
- Genetic diversity and phylogenetic characterization of Newcastle Disease Virus in broilers in Iraq based on the F gene analysis.Open veterinary journal · 2025Article
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Authors and funding
3 authors.
Funding
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Abstract
Background: In poultry, despite intense vaccination programs for prevention of Newcastle disease (ND), the ND infection still affects, causing high mortality in most vaccinated flocks. Aim: This study aimed to determine whether the genetic material of the ND virus has changed and has become incompatible with the vaccines used in Iraq. Methods: Real-time PCR was used to analyze genetic variation in the fusion (F) and haemaggluatination neuraminidase (HN) genes, as well as mRNA expression changes in inflammatory biomarkers, including C-reactive protein (CRP), interleukin 6, interleukin-1 beta (IL-6, IL-1β), and gamma interferon (IFN-γ). Results: Although the Conclusion: ND infection resulted in a decrease in antibody titers and an increase in the expression of inflammatory biomarkers genes. The findings suggested that alterations in the nucleic acids of the NDV strains could be the main cause of potential outbreaks in Iraq, and that vaccines appeared to be incompatible with the circulating strain. Thus, it is recommended that, besides the rapid detection test, molecular methods should always be considered in endemic areas or outbreak situations.
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