ReviewFrontiers in medicine2024
Physical activity and risk of cholelithiasis: a narrative review.
Review in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Exploring the gut-exercise link: A systematic review of gastrointestinal disorders in physical activity.World journal of gastroenterology · 2025Pooled it
- Analysis of factors associated with physical activity in patients with acute pancreatitis: a cross-sectional study in China.Frontiers in physiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholelithiasis, commonly known as gallstone disease, poses a significant public health concern globally, with a myriad of risk factors contributing to its development. Among these, lifestyle factors, particularly physical activity, have garnered considerable attention for their potential role in modulating the risk of gallstone formation. This review aims to synthesize the current landscape of physical activity and the risk of developing cholelithiasis and identify knowledge gaps. To identify relevant articles, an independent author conducted a literature search using the PubMed database including keywords "cholelithiasis," "gallstones," and "physical activity" with no restriction on publication date. Cohort studies or Mendelian randomization analyses that reported physical activity and risk of gallstone disease were included in the current review. 15 articles were included in this review. The review highlights evidence suggesting a protective effect of regular physical activity against the development of gallstones. Results of Mendelian randomization analyses similarly demonstrated that physical activity remains independently causally associated with cholelithiasis. This review underscores the potential of physical activity as a modifiable risk factor for cholelithiasis, advocating for further research to establish definitive guidelines for prevention through lifestyle modification.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.