ArticleOncology letters2025
Primary tracheal hyalinizing clear cell carcinoma with EWSR1 rearrangement: A case report.
Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Extremely rare primary tracheal hyalinizing clear cell carcinoma: two case reports.Translational lung cancer research · 2026Article
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5 authors.
Funding
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Abstract
Hyalinizing clear cell carcinoma (HCCC) is a rare, low-grade epithelial tumor predominantly found in the salivary glands, with tracheal involvement being particularly uncommon. The present study details a case of primary tracheal HCCC and its clinical presentation, diagnostic challenges and the therapeutic approach used. A 34-year-old female patient presented with a 1-month history of intermittent dyspnea. Enhanced chest computed tomography demonstrated a hypervascular nodule occupying two-thirds of the tracheal lumen. Bronchoscopy results showed a mass with significant luminal obstruction. The initial biopsy revealed a poorly differentiated squamous cell carcinoma. The patient underwent surgical resection via a median sternotomy. Histopathology results showed a tumor characterized by trabecular, cord-like and nest-like arrangements within a hyalinized stroma. Immunohistochemistry was positive for carcinoembryonic antigen, cytokeratin (CK)7, CK5/6, pan-CK, epithelial membrane antigen, p40, p63 and p53, with a low Ki-67 index. Fluorescence
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