ArticleJournal of inflammation research2024
Exploring the Regulatory Mechanism of CXCL16 Molecule-Related Antigen Presentation Using lncRNA-mRNA Co-Expression Network Analysis.
Article in Journal of inflammation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Immune and inflammatory mechanisms in asthma: insights into epigenetic modifications.Frontiers in immunology · 2025Pooled it
- Therapeutic target exploration of Shugan Jianpi formula in liver fibrosis: an integrated lncRNA-mRNA co-expression network analysis.Molecular genetics and genomics : MGG · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To investigate the regulatory mechanism of CXCL16 molecule-related Methods: Results: Compared with wild-type mice, CXCL16 knockout mice showed 120 lncRNA and 388 mRNA upregulated in lung tissue, while 1984 lncRNA and 301 mRNA were downregulated. The constructed lncRNA-mRNA co-expression network included 244 differentially expressed lncRNAs and 49 differentially expressed mRNAs. Among them, the core network's expression of the hub gene Idh1 and the top four lncRNAs was validated in the CXCL16 neutralizing antibody asthma model. Conclusion: A comprehensive biological analysis of the lncRNA-mRNA co-expression network explored key genes and pathways, providing new insights for understanding their mechanisms and discovering new targets for asthma induced by
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Registered trials
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