ArticleSleep advances : a journal of the Sleep Research Society2024
Systematic review: differences in complete blood count component rhythms.
Article in Sleep advances : a journal of the Sleep Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Early postoperative "grey zone" gradients following aortic valve replacement surgery: the clinical course and mechanical stress biomarker profile.Surgery today · 2026Observational
- Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Study Objectives: The complete blood count (CBC) is one of the most commonly ordered blood tests with a large range of reference values that does not consider time of day for interpretation. Our objective was to systematically review this topic to report on peak and trough timing of CBC values. Methods: A systematic search was performed for studies evaluating any component of the CBC with at least three collections over 24 hours. The studies were screened based on the predetermined eligibility criteria. Meta-analysis of aggregated data was analyzed with polynomial functions and forest plots. Results: In total, 164 full-text articles were screened and 32 included in the final analysis with 548 total patients considering either leukocytes ( Conclusion: We identified a limited scope of studies characterizing CBC component rhythms. However, we still noted significant differences, particularly with lymphocytes. Future work should evaluate larger datasets to inform time-dependent interpretation of the CBC as we move toward precision medicine.
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