ArticleFrontiers in medicine2024
Association between the heart rate to temperature ratio and 28-day mortality in patients with heart failure in intensive care unit: a multicenter retrospective cohort study.
Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Heart failure (HF) is a life-threatening condition with a high mortality rate. The precise relationship between the heart rate and temperature (HR/T) ratio and mortality in patients with HF remains unclear. This study aimed to investigate the relationship between the HR/T ratio and 28-day intensive care unit (ICU) mortality rates in patients with HF. Methods: This retrospective cohort study analyzed the data of 3,790 patients with congestive heart failure in a large electronic database. Patients were divided into quartiles based on their HR/T ratio: Q1 (1.28-1.76), Q2 (2.44-2.72), Q3 (2.88-3.14), and Q4 (3.29-4.13). Multivariable logistic regression analysis was performed to examine the association between HR/T ratio and 28-day ICU mortality. Results: Patients with higher HR/T ratios had greater disease severity and higher mortality rates. In the fully adjusted regression model, a significant association was observed between HR/T ratio and 28-day ICU mortality risk, with mortality increasing as HR/T ratio rose (OR = 1.55, 95% CI: 1.17-2.04). An E-value analysis indicated that unmeasured confounders had a minimal impact on the results, confirming the robustness of the study. Conclusion: Among ICU-admitted patients with HF, we identified a significant association between HR/T ratio and 28-day ICU mortality. As the HR/T ratio increased, the 28-day ICU mortality showed an upward trend.
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