ReviewJournal of pain research2024
Compression Therapy for Prevention of Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Review in Journal of pain research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Limb Compression Therapy and Chemotherapy-Induced Peripheral Neuropathy in Women With Gynecologic Cancers: A Prospective Self-Controlled Study(NEURO-GLOVE Trial).International journal of cancer · 2026Trial
- Effectiveness of Compression Therapy for the Prevention of Taxane-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis.Journal of pain research · 2026Review
- Article
- PIEZO1: a mechanosensitive ion channel in the pathogenesis and pharmacotherapy of diabetic neuropathy.Molecular biology reports · 2025Review
- Addressing the Needs of Breast Cancer Survivors.Current oncology reports · 2025Review
- Modified Wen Luo Tong Alleviated Chemotherapy-Induced Peripheral Neuropathy via Regulating the CX3CL1/CX3CR1 Axis Through Inhibiting NF-κB and STAT3 Pathways.Integrative cancer therapiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chemotherapy-induced peripheral neuropathy (CIPN) significantly impairs the quality of life of patients undergoing chemotherapy and diminishes their adherence to the treatment regimen. Existing studies suggest that compression therapy may prevent the onset of CIPN, yet the specific efficacy remains to be conclusively determined. Methods: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs) comparing compression therapy with inactive comparators in patients scheduled for chemotherapy. Evidence certainty was evaluated using the GRADE approach. Results: Analysis of four trials (442 patients) revealed that compression therapy reduced CIPN incidence (RR = 0.50, 95% CI: 0.33-0.76; absolute effect = -265, 95% CI: -355 to -127 per 1000) and depression (SMD = -0.83, 95% CI: -1.21 to -0.45) with moderate evidence and high adherence. No significant differences emerged in anxiety, sleep quality, or pain. Conclusion: Moderate- to low-certainty evidence supports compression therapy's effectiveness in preventing CIPN and alleviating depression while showing no substantial impact on other outcomes. Limitation: Evidence quality and quantity suggest potential bias, warranting additional RCTs to strengthen the evidence base.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.