Evidence map›Paper›PMID 39735546›Full record

ArticleFrontiers in immunology2024

Case report: Two cases of pyloric adenomas with high-grade intraepithelial neoplasia at distinct locations.

Yuetian Li, Shuai Chen, Xuechun Zhao, Quanyi Wang

Abstract readCase Reports
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuetian LiClinical School of Medicine, Jining Medical University, Jining, Shandong, China.
Shuai ChenDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.
Xuechun ZhaoClinical School of Medicine, Jining Medical University, Jining, Shandong, China.
Quanyi WangDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rare gastrointestinal tract epithelial polyp known as a pyloric gland adenoma (PGA) is more common in elderly women and uncommon in the duodenum. There are reports of two PGA cases involving high-grade intraepithelial neoplasia. A 75-year-old man was admitted to the hospital as Patient 1 due to "epigastric distension and pain for more than 10 days". The mucous membrane around the stomach fundus and body was thin, and an electron gastroscopy revealed a large, thick protrusion in the stomach fundus that measured about 6 cm in circumference. High-grade intraepithelial neoplasia and stomach pyloric adenoma are the pathological diagnoses. An outside hospital provided consultation for Patient 2, a 68-year-old male. Pyloric adenoma at duodenal bulb with high-grade intraepithelial neoplasia is the pathological diagnosis. The single layer of cuboidal to low columnar epithelial cells with rounded nuclei and eosinophilic cytoplasm was surrounded by densely packed glands with sporadic cystic dilatation that made up the tumor tissue. The diagnosis of PGA required the immunohistochemical labeling of MUC6. In both cases, simple surgical resection was carried out, and followed up for half a year, no recurrence.

Indexed as

AdenomaStomach NeoplasmsAgedCarcinoma in SituGastric MucosaHumansMaleNeoplasm Gradingduodenumgastric adenomahigh-grade intraepithelial neoplasiaimmunohistochemistrypyloric adenoma

Identifiers

PMID39735546
PMCPMC11671352

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