Evidence map›Paper›PMID 39735513›Full record

ArticleNetwork neuroscience (Cambridge, Mass.)2024

Simulated brain networks reflecting progression of Parkinson's disease.

Kyesam Jung, Simon B Eickhoff, Julian Caspers, UKD-PD team, Oleksandr V Popovych

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Network neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kyesam JungInstitute of Neurosciences and Medicine - Brain and Behaviour (INM-7), Research Centre Jülich, 52425 Jülich, Germany.ORCID https://orcid.org/0000-0003-3334-5462
Simon B EickhoffInstitute of Neurosciences and Medicine - Brain and Behaviour (INM-7), Research Centre Jülich, 52425 Jülich, Germany.ORCID https://orcid.org/0000-0001-6363-2759
Julian CaspersDepartment of Diagnostic and Interventional Radiology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.ORCID https://orcid.org/0000-0002-1354-3667
UKD-PD team
Oleksandr V PopovychInstitute of Neurosciences and Medicine - Brain and Behaviour (INM-7), Research Centre Jülich, 52425 Jülich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neurodegenerative progression of Parkinson's disease affects brain structure and function and, concomitantly, alters the topological properties of brain networks. The network alteration accompanied by motor impairment and the duration of the disease has not yet been clearly demonstrated in the disease progression. In this study, we aim to resolve this problem with a modeling approach using the reduced Jansen-Rit model applied to large-scale brain networks derived from cross-sectional MRI data. Optimizing whole-brain simulation models allows us to discover brain networks showing unexplored relationships with clinical variables. We observe that the simulated brain networks exhibit significant differences between healthy controls (

Indexed as

Brain networkParkinson’s diseaseProgressive diseaseWhole-brain model

Identifiers

PMID39735513
PMCPMC11675161

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.