ArticleApplied biosafety : journal of the American Biological Safety Association2024
Determining the Efficacy of Chemicals for the Inactivation of Liquid Waste Containing Gram-Positive Bacteria of Risk Group 2.
Article in Applied biosafety : journal of the American Biological Safety Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background: Inactivation of infectious liquid waste can be performed by different means, including autoclaving or chemical inactivation. Autoclaving is most widely used, but cannot always be implemented, so that chemical inactivation is a possible alternative. However, its efficacy has to be proven by in-house validation. Here, we provide an easy-to-implement validation process adapted from existing standards. Methods: The bactericidal activity of two commercially available disinfectants, containing glucoprotamine or peracetic acid, was tested on two gram-positive bacteria, methicillin-resistant Results: Peracetic acid was highly efficient against both strains, even at a working concentration of 0.25% for 1 minute Conclusion: We could confirm the very high efficacy of glucoprotamine- and peracetic-based disinfectants to inactivate liquid waste containing gram-positive bacteria. Also considering aquatic toxicity, this methodology could help laboratories to establish validated procedures for chemical inactivation of infectious liquid wastes relevant to their institution, balancing efficacy, and environmental issues.
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