ArticleWorld journal of gastrointestinal endoscopy2024
Extended 72-hour patency capsule protocol improves functional patency rates in high-risk patients undergoing capsule endoscopy.
Article in World journal of gastrointestinal endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Retention of Small Bowel Capsule in a Patient With Remote Small Bowel Resection With a Normal CT Enterography and Patency Capsule Examination.Case reports in surgery · 2026Article
- Device-assisted enteroscopy: With increasing requirements, national Irish data support a centralized high-volume model to achieve performance targets.Endoscopy international open · 2026Article
- Artificial intelligence-augmented small bowel capsule endoscopy for coeliac disease: a literature review on accuracy, workflow, and safety.Translational gastroenterology and hepatology · 2026Review
- Marking 25 years of capsule endoscopy: from bold innovation to enduring legacy.Therapeutic advances in gastrointestinal endoscopyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCapsule endoscopy (CE) is a pivotal diagnostic tool for gastrointestinal (GI) disorders, yet capsule retention poses a significant risk, especially in patients with known risk factors. The patency capsule (PC) helps assess the functional patency of the GI tract to mitigate this risk. However, the standard 28-hour protocol for confirming patency often results in high false-positive rates, unnecessarily excluding many patients from undergoing diagnostic CE.
aimTo investigate the use of a 72-hour extended patency protocol to improve functional patency rates in patients at risk of capsule retention.
methodsWe performed a prospective, open-label study evaluating an extended 72-hour protocol for confirming functional patency with the PC. Conducted over six months, 135 patients with risk factors for capsule retention were enrolled. The primary endpoint was the capsule retention rate in patients with confirmed functional patency. Secondary endpoints included the rates of confirmed patency
resultsFunctional patency was confirmed in 48.9% (
conclusionExtending the patency assessment protocol to 72 hours significantly improves the rate of confirmed functional patency without increasing the risk of capsule retention. This protocol is safe, effective, and cost-neutral, allowing more patients to benefit from CE. Further studies are recommended to refine the protocol and enhance its clinical utility.
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