Evidence map›Paper›PMID 39735306›Full record

ArticleACS central science2024

From Beam Damage to Massive Reaction Amplification under the Electron Microscope: An Ionization-Induced Chain Reaction in Crystals of a Dewar Benzene.

Krzysztof A Konieczny, Indrajit Paul, Jose A Rodriguez, Miguel A Garcia-Garibay

Abstract read
In one paragraph

Article in ACS central science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Krzysztof A KoniecznyDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.ORCID https://orcid.org/0000-0003-4618-5154
Indrajit PaulDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.ORCID https://orcid.org/0000-0002-5526-8106
Jose A RodriguezDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.ORCID https://orcid.org/0000-0002-0248-4964
Miguel A Garcia-GaribayDepartment of Chemistry and Biochemistry, University of California at Los Angeles, Los Angeles, California 90095, United States.ORCID https://orcid.org/0000-0002-6268-1943

Funding

Micro Electron Diffraction of Toxic and/or Infectious Macromolecular NanoassembliesR35GM128867 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Jose Alfonso Rodriguez · 2018 to 2026
$3.1M
NIGMS NIH HHS R35 GM128867
6 · The paper itself

Abstract

Electron microscopy in its various forms is one of the most powerful imaging and structural elucidation methods in nanotechnology where sample information is generally limited by random chemical and structural damage. Here we show how a well-selected chemical probe can be used to transform indiscriminate chemical damage into clean chemical processes that can be used to characterize some aspects of the interactions between high-energy electron beams and soft organic matter. Crystals of a Dewar benzene exposed to a 300 keV electron beam facilitate a clean valence-bond isomerization radical-cation chain reaction where the number of chemical events per incident electron is amplified by a factor of up to ca. 90,000.

Identifiers

PMID39735306
PMCPMC11672530

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.