Evidence map›Paper›PMID 39735272›Full record

ArticleWorld journal of gastroenterology2024

N6-methyladenosine-modified long non-coding RNA

Yong Yu, Xiang-Hong Lu, Jin-Song Mu, Jiang-Yun Meng, Jiang-Shan Sun, Hai-Xu Chen, Yang Yan, Ke Meng

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yong YuDepartment of Gastroenterology and Hepatology, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Xiang-Hong LuDepartment of Intensive Care Medicine, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Jin-Song MuDepartment of Intensive Care Medicine, The Fifth Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100039, China.
Jiang-Yun MengDepartment of Gastroenterology and Hepatology, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Jiang-Shan SunDepartment of Gastroenterology and Hepatology, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Hai-Xu ChenInstitute of Geriatrics and National Clinical Research Center of Geriatrics Disease, The Second Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Yang YanDepartment of General Surgery, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Ke MengDepartment of Gastroenterology and Hepatology, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing 100853, China. mengke301@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHepatocellular carcinoma (HCC) is a prevalent and aggressive tumor. Sorafenib is the first-line treatment for patients with advanced HCC, but resistance to sorafenib has become a significant challenge in this therapy. Cancer stem cells play a crucial role in sorafenib resistance in HCC. Our previous study revealed that the long non-coding RNA (lncRNA)

aimTo describe the role of the lncRNA

methodsTumor tissue and adjacent non-cancerous tissue samples were collected from HCC patients. Sphere formation was quantified

resultsCompared with that in normal controls, the expression of the lncRNA

conclusionThe N6-methyladenosine-modified lncRNA

Indexed as

AdenosineCarcinoma, HepatocellularDrug Resistance, NeoplasmGene Expression Regulation, NeoplasticLiver NeoplasmsNeoplastic Stem CellsRNA, Long NoncodingSorafenibUp-RegulationAnimalsAntineoplastic AgentsApoptosisCell Line, TumorCell ProliferationFemaleHomeodomain ProteinsAdenosineAntineoplastic AgentsHomeodomain ProteinsMethyltransferasesMETTL3 protein, humanN-methyladenosineRNA, Long NoncodingSorafenibHepatocellular carcinomaLong non-coding RNA KIF9-AS1Short stature homeobox 2Sorafenib resistanceStemness

Identifiers

PMID39735272
PMCPMC11612700

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.