Evidence map›Paper›PMID 39735199›Full record

ArticleProstate international2024

Weekly versus 2-weekly versus 3-weekly docetaxel to treat metastatic castration-resistant prostate cancer.

Hyeong Dong Yuk, Miso Kim, Bhumsuk Keam, Ja Hyeon Ku, Cheol Kwak, Chang Wook Jeong

Abstract read
In one paragraph

Article in Prostate international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hyeong Dong YukDepartment of Internal Urology, College of Medicine, Seoul National University, Seoul, Korea.
Miso KimDepartment of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea.
Bhumsuk KeamDepartment of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea.
Ja Hyeon KuDepartment of Internal Urology, College of Medicine, Seoul National University, Seoul, Korea.
Cheol KwakDepartment of Internal Urology, College of Medicine, Seoul National University, Seoul, Korea.
Chang Wook JeongDepartment of Internal Urology, College of Medicine, Seoul National University, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To compare the efficacy and toxicity of docetaxel treatment regimens in metastatic castration-resistant prostate cancer (mCRPC). Methods: We retrospectively analyzed 162 patients diagnosed with mCRPC who underwent docetaxel chemotherapy between 2009 and 2020. The patients were divided into three groups according to the dosage and interval of docetaxel (DCT) chemotherapy regimen: 30 mL/m Results: There were no significant differences in the prostate-specific antigen (PSA) response rates ( Conclusions: The various options for optimal chemotherapy are indicated depending on the patient's conditions during the diagnosis of mCRPC. Treatment with DCT at 2-week or even 1-week intervals appears to be well tolerated in men diagnosed with mCRPC and represents a useful option when the conventional triweekly regimen is not tolerated due to poor patient condition.

Indexed as

BiweeklyChemotherapyDocetaxelMetastatic castration-resistant prostate cancerProstate cancer

Identifiers

PMID39735199
PMCPMC11681325

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.