An Atypical Manifestation: Linear Hyperkeratotic Prurigo Nodularis.

Sanjana Likki, Iman Ali, T Austin Black, Noel X Yang, Emelie N McQuitty, Rashid M Rashid

Abstract readCase Reports

In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sanjana LikkiDermatology, University of Texas Health Science Center at Houston, John P. and Katherine G. McGovern Medical School, Houston, USA.

Iman AliDermatology, University of Texas Health Science Center at Houston, John P. and Katherine G. McGovern Medical School, Houston, USA.

T Austin BlackDermatology, University of Texas Health Science Center at Houston, John P. and Katherine G. McGovern Medical School, Houston, USA.

Noel X YangDermatology, University of Texas Health Science Center at Houston, John P. and Katherine G. McGovern Medical School, Houston, USA.

Emelie N McQuittyDermatology, University of Texas Health Science Center at Houston, John P. and Katherine G. McGovern Medical School, Houston, USA.

Rashid M RashidDermatology, Mosaic Dermatology, Houston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 42-year-old Indian male with prurigo nodularis, exhibiting multiple verrucous, brownish-black nodules on the left lower and right upper extremities, with milder involvement of the right lower extremity. The lesions were asymmetrically distributed in a near-linear pattern, with prominent white hyperkeratosis and associated moderate pruritus and paresthesia. Differential diagnoses included pemphigoid nodularis, verruca vulgaris, and hypertrophic lichen planus, with a biopsy confirming prurigo nodularis. While prurigo nodularis typically presents with symmetric dome-shaped nodules on extensor surfaces, the asymmetric distribution, near-linear arrangement, and verrucous texture observed here are unusual and underscore the importance of recognizing prurigo nodularis variants to ensure accurate diagnosis and effective management.

Indexed as

dupilumabhyperkeratosispruigo nodularisprurigopruritusskin nodules

Identifiers

PMID39735054

DOI10.7759/cureus.74588

PMCPMC11674318

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