Evidence map›Paper›PMID 39735050›Full record

ReviewCureus2024

Cancer: A Disease of Modern Times?

Natasha Nwosu

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Natasha NwosuOncology, University College London Hospitals NHS Foundation Trust, London, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is a leading cause of mortality worldwide. Despite its prevalence, its origins remain a topic of debate, sparking discussion within the medical and historical professions. It had been feared for centuries, initially perceived as an incurable condition fraught with social stigma. This review details the historical records of cancer, tracing its earliest documented cases in ancient Egyptian and Greek civilizations, and follows the evolution of oncology treatment. Advances in medical technology and screening methods may have led to improved detection of cancer, with conditions that may have gone unnoticed in the past now diagnosed more frequently. Hippocrates and Galen later advanced the understanding of cancer by shifting from supernatural theories to a more scientific approach. The role of modifiable risk factors is highlighted, as well as the controversy surrounding the concept that cancer is a product of modern times. Environmental influences such as air pollution and tobacco smoke have been identified as carcinogenic, with public health campaigns subsequently developed. Whilst these preventative efforts aim to reduce such risks, evidence suggests that the causes of cancer are likely multi-faceted and, therefore, focusing solely on industrial factors may simplify a complex issue. The discussion remains open as to whether cancer is truly the product of modern industrialisation, or whether its low incidence in the past was due to less effective documentation and understanding. The apparent low prevalence of cancer in ancient times raises questions about the role of carcinogenic environmental factors in modern societies, with a need for continued research to explore its true origins and, therefore, develop effective strategies for prevention and treatment.

Indexed as

modern industrialisationmodifiable risk factorsorigins of cancerpopulation healthtobacco smoke

Identifiers

PMID39735050
PMCPMC11681836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.