Evidence map›Paper›PMID 39734985›Full record

ArticleCureus2024

Radiofrequency Ablation for Unstable Ruptured Hepatocellular Carcinoma: A Case Report and Literature Review.

Matteo Pagani, Carla Tasca, Rosita De Vincenti, Massimo Fedi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matteo PaganiGeneral Surgery, University of Florence, Florence, ITA.
Carla TascaGeneral Surgery, University of Florence, Florence, ITA.
Rosita De VincentiHepatobiliary Surgery, USL Toscana Centro, Pistoia, ITA.
Massimo FediHepatobiliary Surgery, USL Toscana Centro, Pistoia, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous liver bleeding is a rare but life-threatening complication of hepatocellular carcinoma (HCC). The optimal management strategy for this condition remains a topic of ongoing debate. We present the case of a 74-year-old man with cirrhosis and hemorrhagic shock resulting from the spontaneous rupture of HCC. Following a contrast-enhanced CT scan, the patient underwent emergency laparotomy. Hemostasis was attempted using conventional techniques but was unsuccessful. Due to unstable conditions (low blood pressure and high heart rate), poor liver function reserve, and a multifocal tumor, we decided to perform ultrasound-guided radiofrequency ablation (RFA) to achieve hemostasis. The patient was admitted to the ICU for early postoperative monitoring. On the second postoperative day, the patient returned to the surgical department. In most cases, interventional treatment is necessary to achieve hemostasis, even in patients with Child-Pugh C liver function. While transarterial chemoembolization followed by staged hepatectomy is considered the treatment of choice based on current clinical evidence, RFA is a viable alternative. In this case report, we demonstrate that RFA is a safe and effective technique for achieving hemostasis. It should be considered as an option for selected patients with ruptured HCC who are hemodynamically unstable, when embolization or resection is unavailable or unfeasible due to the patient's condition, or in cases of end-stage liver disease.

Indexed as

case reportemergency laparotomyhepatocellular carcinoma ruptureliver bleedingradiofrequency ablation (rfa)

Identifiers

PMID39734985
PMCPMC11676332

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.