Evidence map›Paper›PMID 39734944›Full record

ArticleCureus2024

Spindle Cell Carcinoma of the Larynx Arising From Aggressive Fibromatosis.

Vedika Dhunnoo, Richard Stevens, Andrew Kinshuck

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vedika DhunnooOtolaryngology - Head and Neck Surgery, Liverpool University Foundation Trust, Liverpool, GBR.
Richard StevensOtolaryngology - Head and Neck Surgery, Liverpool University Foundation Trust, Liverpool, GBR.
Andrew KinshuckOtolaryngology - Head and Neck Surgery, Aintree University Hospital, Liverpool, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aggressive fibromatosis is a rare, benign proliferative disease with unknown aetiology and high recurrence rate. To date, there are only eight reported cases affecting the larynx. Four were managed with total laryngectomy, whilst spontaneous regression happened in one case. Spindle cell carcinoma is a rare but highly aggressive biphasic tumour which often arises in the head and neck. Diagnosed with laryngeal fibromatosis more than 10 years ago, our patient had undergone six trans-oral laser debulking procedures. On this occasion, he presented with a two-week history of severe worsening dyspnoea and hoarseness of voice, requiring urgent debulking. Final pathology results revealed spindle cell carcinoma of the larynx. In this report, we describe the case of laryngeal fibromatosis which progressed to spindle cell carcinoma. To our knowledge, no such case has been described previously. This case highlights an important complication of laryngeal fibromatosis and emphasises the importance of regular follow-ups.

Indexed as

carcinoma of larynxlaryngeal fibromatosismasslike lesion in the larynxotolaryngologyspindle cell neoplasm

Identifiers

PMID39734944
PMCPMC11682534

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.