Evidence map›Paper›PMID 39734937›Full record

ArticleCureus2024

Glasgow Prognostic Score and Outcomes in Elderly Head and Neck Cancer Surgery With Free-Flap Reconstruction: A Retrospective Study.

Keitaro Nagano, Kiyomi Kuba, Masami Osaki, Akio Hatanaka, Mutsuko Hara, Kazue Manaka, Shingo Kinoshita, Mitsumura Kazuhiro, Ryohei Mukae, Masaya Umino

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Keitaro NaganoDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Kiyomi KubaDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Masami OsakiDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Akio HatanakaDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Mutsuko HaraDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Kazue ManakaDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Shingo KinoshitaDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Mitsumura KazuhiroDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Ryohei MukaeDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.
Masaya UminoDepartment of Otolaryngology, Head and Neck Surgery, Ageo Central General Hospital, Ageo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Determining good candidates for head and neck cancer surgery in elderly patients requires consideration of various factors, such as overall health and social background, yet specific evaluation guidelines are lacking. The Glasgow Prognostic Score (GPS) is a marker used to assess nutritional status and prognosis in cancer patients. Objective This study aims to evaluate the association between the GPS and both the prognosis and postoperative complications in reconstructive surgery cases for head and neck cancer in patients aged 80 and over. Materials and methods A total of 22 patients aged 80 and over who underwent reconstructive surgery in our department between January 2011 and December 2023 were included. Patients were divided into three groups based on their preoperative GPS scores (0, 1, and 2 points). The overall survival was evaluated using the Kaplan-Meier method. The Cox proportional hazards model was used to analyze the association between GPS and prognosis, adjusting for confounders such as malnutrition, primary site, and comorbidities. The association between GPS and perioperative complications classified as Clavien-Dindo grade 3 or higher was also examined. Results The mean age was 82.2 years, and 20 (90%) of the subjects had comorbidities. Higher GPS scores were associated with lower survival rates, and GPS was an independent prognostic factor. There was no significant association between GPS and perioperative complications of grade 3 or higher. Conclusion The GPS is a useful prognostic indicator in elderly patients undergoing reconstructive surgery for head and neck cancer. However, a comprehensive evaluation such as the Geriatric 8, along with more inclusive malnutrition criteria, is recommended for an overall assessment of good candidates for the procedure.

Indexed as

elderly patientsfree flap-oral cancergeriatric assessmentglasgow prognostic scoreglim criteriagpshead and neck cancerpostoperative complicationsprognosisreconstructive surgery

Identifiers

PMID39734937
PMCPMC11682163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.