Evidence map›Paper›PMID 39734878›Full record

ArticleMedical journal, Armed Forces India2024

Pyrethroid poisoning: Insecticide with mild human toxicity.

Ramya Iyadurai, J V Peter, Audrin Lenin, Bijesh Yadav, Alex Reginald, K P P Abhilash, J V Punitha, Samuel George Hansdak

Abstract read
In one paragraph

Article in Medical journal, Armed Forces India, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ramya IyaduraiProfessor, Medicine (Unit 5), Christian Medical College, Vellore, Tamilnadu, India.
J V PeterProfessor (Intensive Care), Christian Medical College, Vellore, Tamilnadu, India.
Audrin LeninAssistant Professor, Medicine (Unit 3), Christian Medical College, Vellore, Tamilnadu, India.
Bijesh YadavSenior Demonstrator (Biostatistics), Christian Medical College, Vellore, Tamilnadu, India.
Alex ReginaldProfessor (Medicine), Christian Medical College, Vellore, Tamilnadu, India.
K P P AbhilashProfessor (Accident & Emergency Medicine), Christian Medical College, Vellore, Tamilnadu, India.
J V PunithaProfessor, Medicine (Unit 1), Christian Medical College, Vellore, Tamilnadu, India.
Samuel George HansdakProfessor, Medicine (Unit 4), Christian Medical College, Vellore, Tamilnadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pyrethroid insecticides are commonly used insecticides. This study was undertaken to characterize the clinical profile and outcome of deliberate self-harm (DSH) with type 1 and type 2 pyrethroids and identify factors associated with need for hospitalization. Methods: This retrospective study was conducted in a tertiary care hospital in South India to study the clinical features, treatment, and outcome of patients with pyrethroid poisoning due to DSH. Patients were categorized as poisoning with type 1 or type 2 pyrethroid compounds. Factors associated with need for hospital admission was explored using bivariate and multivariate regression analysis and expressed as odds ratio (OR) with 95% confidence intervals (CIs). Results: A total of 379 patients presented with pyrethroid poisoning; 202 (53.3%) patients were male. The median (interquartile range) age was 26 (22-33) years. Transfluthrin (n = 48, 58%) and cypermethrin (n = 149, 50%) were the most frequently implicated type 1 compounds and type 2 compounds, respectively. Of the 130 (34.3%) patients who were admitted, 13 (3.4%) patients required mechanical ventilation. All patients survived. On multivariate logistic regression analysis, ingestion of type 2 pyrethroids (OR: 2.55, 95%CI: 1.31-4.97), history of seizures (OR: 2.62, 95%CI 1.06-6.48), and treatment prior to presentation to the referral hospital (OR: 2.99, 95%CI: 1.87-4.74) were associated with the need for hospitalization. Conclusion: A third of patients with pyrethroid poisoning require hospitalization. Type 2 pyrethroid poisoning is more frequent in clinical practice. Ingestion of type 2 pyrethroids, seizures, and need for pre-hospital treatment are associated with hospitalization.

Indexed as

Human toxicityOutcomesPyrethroidType 1/type 2 pyrethroid compounds

Identifiers

PMID39734878
PMCPMC11670549

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