Evidence map›Paper›PMID 39734867›Full record

ArticleMedical journal, Armed Forces India2024

Prevalence and impact of obstructive sleep apnea in type 2 diabetes mellitus: A descriptive cross-sectional study.

Puneet Saxena, Dharmendra Singh, Yashpal Singh

Abstract read
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Article in Medical journal, Armed Forces India, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Puneet SaxenaClassified Specialist (Respiratory Medicine), Army Hospital (R&R), New Delhi, India.
Dharmendra SinghGraded Specialist (Medicine), 178 Military Hospital, C/o 99 APO, India.
Yashpal SinghCommandant, Military Hospital, Jabalpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Obstructive sleep apnea (OSA) has been reported to have a high prevalence in patients with type 2 diabetes mellitus. There is scarcity of literature on relationship between OSA and diabetes in Indian population. Methods: A cross-sectional observational study was conducted at a tertiary care hospital and 80 consecutive and consenting patients with diabetes were enrolled over 24 months from 01 Sep 2014 to 31 Aug 2016. After a detailed history and clinical examination, all patients were subjected to a level I polysomnography (PSG), and their blood sample was drawn for the assessment of diabetes control, insulin resistance, and microvascular complications. Results: Out of 80 patients with diabetes, 30 (37.5%) patients had a high-risk score on Berlin questionnaire and 59 (73.8%) patients had evidence of OSA by PSG. The prevalence of OSA in diabetics with normal body mass index, waist circumference, and neck circumference was 65.5%, 64.2%, and 67.2%, respectively. Patients with OSA had a significantly higher mean glycosylated hemoglobin (correlation coefficient 0.53) and higher insulin resistance (correlation coefficient 0.78). Patients with microvascular complications had a higher prevalence of OSA than those without. This included neuropathy (100% versus 62.5%), retinopathy (100% versus 69.6%) and diabetic kidney disease (DKD) (90.9% versus 52.8%). Patients with any microvascular complication were significantly more likely to have OSA (odds ratio 13.66, 95% confidence interval 3.94-47.37, p < 0.001). Conclusion: Indian patients with diabetes have a high prevalence of OSA, regardless of obesity. Patients with diabetes and OSA have poorer diabetes control, more insulin resistance, and higher prevalence of microvascular complications like nephropathy, neuropathy, and retinopathy.

Indexed as

Diabetes mellitusMicrovascular complicationsObstructive sleep apneaPolysomnography

Identifiers

PMID39734867
PMCPMC11670581

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