ReviewBiomaterials translational2024
Stimuli-responsive hydrogels for bone tissue engineering.
Review in Biomaterials translational, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
27 citing papers in PubMed.
- Smart and stimuli-responsive hydrogels for controlled exosome delivery in bone tissue engineering: from passive carriers to intelligent therapeutic platforms.Cell and tissue banking · 2026Review
- Aptamer-Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- From disease model to therapeutic insight: An engineered hydrogel reveals the role of matrix viscous dissipation in intervertebral disc degeneration.Bioactive materials · 2026Article
- Advances in GelMA Hydrogel-Enabled Angiogenic-Osteogenic Coupling: From Structural Programming to Exogenous Cue Synergy.Journal of functional biomaterials · 2026Review
- Smart Microneedles Regulate Reactive Oxygen Species and Deliver Matrix Metalloproteinases for Pathological Scar Treatment.ACS nano · 2026Article
- High-performance hydrogels in orthopedics: Structural design, performance tuning, and clinical potential.Materials today. Bio · 2026Review
- Highly bio-adapted hydrogels for tendon-bone interface regeneration: Natural healing inspiration, design strategies, and biomedical potential.Bioactive materials · 2026Review
- Hydrogels for Bone Repair: Construction Strategies and Applications.Smart medicine · 2026Review
- Advanced multifunctional thermo- and electro-stimulative hydrogels for bone regeneration.Materials today. Bio · 2026Review
- Multifunctional implantable hydrogels: Smart platforms at the forefront of biomedical innovation.Materials today. Bio · 2026Review
- Piezoelectric scaffold with enhanced effect drives the healing of osteochondral defects through electromechanical-immune coupling.Journal of nanobiotechnology · 2026Article
- 4D-printed Fe3O4-PLLA scaffolds modulate osteoimmune microenvironment for oral bone repair.Materials today. Bio · 2026Article
- Advances in polymer-based hydrogel systems for adipose-derived mesenchymal stem cells toward bone regeneration.World journal of orthopedics · 2026Review
- Smart biomaterials in regenerative medicine.Biomaterials translational · 2026Article
- Piezoelectric scaffolds for bone regeneration: a systematic review of preclinical studies.Frontiers in bioengineering and biotechnology · 2026Review
- Biocompatible Stimuli-Sensitive Natural Hydrogels: Recent Advances in Biomedical Applications.Gels (Basel, Switzerland) · 2025Review
- Rat Calvarial Guided Bone Regeneration Model: Preclinical Insights into Biomaterials, Barrier Design, and Systemic Modulators.Journal of functional biomaterials · 2025Review
- Review
- One-step strategy for fabricating icariin-encapsulated biomimetic Scaffold: Orchestrating immune, angiogenic, and osteogenic cascade for enhanced bone regeneration.Bioactive materials · 2025Article
- An Autologous Human Adipose Stem Cell-Derived 3D Osteogenic Implant for Bone Grafting: From Development to First-in-Human Experience.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The treatment of bone defects remains a great clinical challenge. With the development of science and technology, bone tissue engineering technology has emerged, which can mimic the structure and function of natural bone tissues and create solutions for repairing or replacing human bone tissues based on biocompatible materials, cells and bioactive factors. Hydrogels are favoured by researchers due to their high water content, degradability and good biocompatibility. This paper describes the hydrogel sources, roles and applications. According to the different types of stimuli, hydrogels are classified into three categories: physical, chemical and biochemical responses, and the applications of different stimuli-responsive hydrogels in bone tissue engineering are summarised. Stimuli-responsive hydrogels can form a semi-solid with good adhesion based on different physiological environments, which can carry a variety of bone-enhancing bioactive factors, drugs and cells, and have a long retention time in the local area, which is conducive to a long period of controlled release; they can also form a scaffold for constructing tissue repair, which can jointly promote the repair of bone injury sites. However, it also has many defects, such as poor biocompatibility, immunogenicity and mechanical stability. Further studies are still needed in the future to facilitate its clinical translation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.