Evidence map›Paper›PMID 39734670›Full record

ArticleFrontiers in nutrition2024

Handgrip strength and body mass index exhibit good predictive value for sarcopenia in patients on peritoneal dialysis.

Hongyan Li, Yuanhua Zheng, Yuanyuan Zhang, Xiaotian Zhang, Wei Luo, Weiyi Zhu, Yaqing Zhang

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Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hongyan LiSchool of Nursing, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuanhua ZhengPeritoneal Dialysis Center, The First Affiliated Hospital, Nanchang University, Nanchang, China.
Yuanyuan ZhangSchool of Nursing, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaotian ZhangSchool of Nursing, Jiangxi Medical College, Nanchang University, Nanchang, China.
Wei LuoDepartment of Nursing, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi, China.
Weiyi Zhu *Department of Nursing, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yaqing Zhang *School of Nursing, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: The diagnosis of sarcopenia in patients on peritoneal dialysis (PD) in clinics is limited owing to its relatively complicated process and the need for expensive assessment equipment. This study aimed to develop and validate sex-specific nomogram models based on body mass index (BMI), handgrip strength, and other routine follow-up examination indicators to predict sarcopenia in patients on PD. Methods: From March 2023 to February 2024, 699 eligible patients were recruited from the PD centers of two tertiary hospitals in southeastern China. Routine follow-up examination indicators such as age, BMI, biochemical indicators, dialysis adequacy, handgrip strength, and five-repetition sit-to-stand test, were used as potential predictive variables. Multivariate logistic regression analyses were used to separately determine the predictive factors for men and women. Nomogram models were constructed based on the results of the multivariate analyses, which were internally validated using a bootstrap re-sampling method ( Results: The prevalence of sarcopenia in Chinese patients on PD was 13.92%. The nomogram models based on multivariate analyses revealed both handgrip strength and BMI as independent predictors of sarcopenia in men and women on PD. The bootstrap-corrected area under the ROC curves of the models was 0.924 (95% CI: 0.888-0.959) and 0.936 (95% CI, 0.906-0.966) for men and women, respectively. The calibration curves of both models demonstrated high consistency between the observed and anticipated values. Conclusion: The two nomogram models based on BMI and handgrip strength demonstrated good predictive ability for sarcopenia in male and female patients on PD. Subsequently, these may be used as convenient and inexpensive methods for the early detection and timely management of sarcopenia in patients on PD.

Indexed as

body mass indexhandgrip strengthnomogramperitoneal dialysisrisk factorssarcopenia

Identifiers

PMID39734670
PMCPMC11671354

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