Evidence map›Paper›PMID 39734622›Full record

ReviewTH open : companion journal to thrombosis and haemostasis2024

Why Current Detection of Vascular Calcification Falls Short and How to Improve on It.

Anouk Gentier, Mueez Aizaz, Maurice Halder, Alexandru Florea, Ingrid Dijkgraaf, Felix M Mottaghy, Tilman Hackeng, M Eline Kooi

Abstract readReview
In one paragraph

Review in TH open : companion journal to thrombosis and haemostasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anouk GentierDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University Maastricht, Maastricht, The Netherlands.ORCID 0009-0000-3818-8238
Mueez AizazCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
Maurice HalderDepartment for Renal and Hypertensive, Rheumatological and Immunological Diseases (Department of Medicine II), RWTH Aachen, Medical Faculty, Aachen, Germany.
Alexandru FloreaCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
Ingrid DijkgraafDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University Maastricht, Maastricht, The Netherlands.
Felix M MottaghyCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.
Tilman HackengDepartment of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), University Maastricht, Maastricht, The Netherlands.
M Eline KooiCardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.ORCID 0000-0001-7562-5724

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vascular calcification is a common phenomenon in various vascular diseases, where its presence heralds increased occurrence of adverse disease events, which invariably lead to increased morbidity and mortality in patients. Although the impact of calcification has become apparent, adequate and early detection of the most damaging form of early microcalcification is still in its infancy, preventing reliable identification of locations that would benefit from intervention. In this review, we will provide an overview of the current state-of-the-art noninvasive calcification imaging and its persisting limitations. We discuss promising approaches that may address these limitations in the future. In this context particular attention will be paid to imaging modalities such as CT, PET, and ultrasonography and molecular and cellular mechanisms and agents involved in physiological bone formation.

Indexed as

cardiovascular diseaseearly detectionimagingnoninvasive imagingvascular calcification

Identifiers

PMID39734622
PMCPMC11679638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.