Evidence map›Paper›PMID 39734420›Full record

ArticleJournal of oral biology and craniofacial research

Evaluation of osteoblast response to polyacrylonitrile infused nano-curcumin coated on titanium discs: Invitro study cell culture experimental study.

Shilpi Gupta, N Gopi Chander, Aravind Bhatt, K V Anitha

Abstract read
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Potential mechanism of gingerFrontiers in pharmacology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shilpi GuptaDepartment of Prosthodontics, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, 89, India.
N Gopi ChanderDepartment of Prosthodontics, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, 89, India.
Aravind BhattDepartment of Prosthodontics, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, 89, India.
K V AnithaDepartment of Prosthodontics, SRM Dental College, Bharathi Salai, Ramapuram, Chennai, 89, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The study evaluated the influence of titanium discs, coated with polyacrylonitrile infused curcumin nanofibers on osteoblast activity. Materials and methods: The titanium discs were coated with polyacrylonitrile nanofibers infused with curcumin. MG-63 cell lines were utilized for cell culture to assess osteoblast morphology upon exposure of curcumin on titanium discs. SEM comparison was made. Lactate Dehydrogenase (LDH) activity was measured after 2 and 7 days and the Alkaline Phosphatase (ALP) activity of the cells was quantified. Results: The results indicated that the coating had a notable impact on mineralization, LDH and ALP activities. Significant differences were observed between uncoated and coated samples. The SEM analysis indicated that curcumin enhanced bone growth when the Ti discs coated with curcumin are implanted in the bone. Conclusion: Polyacrylonitrile infused nano-curcumin fibers coated on titanium discs potentially enhanced osteoblast response and mineralization.

Indexed as

CurcuminSurface coatingTitanium disc

Identifiers

PMID39734420
PMCPMC11681823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.