ArticleTurkish journal of medical sciences2024
Association between papillary thyroid cancer and
Article in Turkish journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Background/aim: To investigate the association between the rs2267437, rs5751129 and rs132770 polymorphisms of the Materials and methods: The study included 150 patients who had been diagnosed with PTC and 204 healthy controls. Genotyping of the SNPs was performed using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: In the rs2267437 polymorphism, individuals with the GG genotype had lower risk of PTC than those with the wild-type CC genotype (p = 0.037, 95% CI: 0.19-0.96, OR: 0.67). The combined genotypes CG+GG were related to a reduced risk of PTC compared to the wild-type CC genotype (p = 0.023, 95% CI: 0.40-0.94, OR: 0.61) in the recessive model (GC+GG vs. CC). In addition, a query of the genotype-tissue expression (GTEx) database showed that the rs2267437 polymorphism may alter the expression level of Conclusion: This study demonstrated that rs2267437 polymorphism may have a protective effect against PTC in the Turkish population. However, the rs5751129 and rs132770 polymorphisms were not associated with the disease.
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