Evidence map›Paper›PMID 39733411›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2024

Performance of HPV Self-Sample Collected by a Novel Kit in Comparison with Clinician Collected Sample for Cervical Cancer Screening.

Smita Joshi, B Kishore Kumar, Vijayalakshmi Ramshankar, Nandita Maitra, Sayantani Pramanik Palit, Soundharya Ravindran, Twinkle Sara Shyam

Abstract readComparative Study
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Smita JoshiDepartment of Preventive Oncology, Prayas, Amrita Clinic, Pune, India.ORCID 0000-0003-4776-2275
B Kishore KumarConsilx Digital, India.
Vijayalakshmi RamshankarDepartment of Cancer Biology and Molecular Diagnostics, Cancer Institute WIA, Adyar, India.ORCID 0000-0001-6890-4231
Nandita MaitraDepartment of Obstetrics and Gynaecology, Baroda Medical college and Sir Sayajirao General Hospital, Baroda, India.
Sayantani Pramanik PalitPragmatech Healthcare Solutions Pvt. Ltd., Vadodara, Gujarat, India.
Soundharya RavindranDepartment of Cancer Biology and Molecular Diagnostics, Cancer Institute WIA, Adyar, India.
Twinkle Sara ShyamDepartment of Obstetrics and Gynaecology, Baroda Medical college and Sir Sayajirao General Hospital, Baroda, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesWe are reporting the performance of HPV self-sample collected by a novel kit in comparison with clinician collected cervical sample for HPV testing for cervical cancer screening.

methodsConsenting, eligible women aged 25 to 60, with a positive cervical cancer screening test report in the past one year but without any prior treatment for cervical abnormalities were enrolled in the study. Each woman provided 2 samples for the HPV test (vaginal self-sample collected with the CERVICHECKTM, an indigenous kit from India and cervical sample collected by the clinician). These samples were analysed using cobas HPV test on 4800 platform and for liquid-based cytology.

resultsWe enrolled 156 eligible, consenting participants at 2 study sites. The agreement for the sample collected by CERVICHECKTM and clinician collected sample for any high-risk HPV was 95.1% (k= 0.90, SE 0.036, 95% CI 0.83-0.97). The agreement for HPV 16 or 18 only was 95.1%, (k=0.88, SE 0.045, 95% CI 0.79-0.97). The overall acceptability of the kit was good, participants expressed that self-sampling was easy and > 90% women were willing to recommend it to their friends. INTERPRETATION AND

conclusionsThere was almost perfect or perfect agreement between the HPV self-sample collected by CERVICHECKTM and clinician collected cervical sample. Self-sampling was highly acceptable to the participating women.

Indexed as

Early Detection of CancerPapillomavirus InfectionsSpecimen HandlingUterine Cervical NeoplasmsVaginal SmearsAdultDNA, ViralFemaleFollow-Up StudiesHumansMiddle AgedPapillomaviridaePrognosisReagent Kits, DiagnosticDNA, ViralReagent Kits, DiagnosticCervical cancercervical cancer screeningHPVself-sample

Identifiers

PMID39733411
PMCPMC12008359

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.