Evidence map›Paper›PMID 39733225›Full record

ArticleMedicine and science in sports and exercise2025

Clinical Measures Associated with Subsequent Injury after Adolescent Concussion: A Prospective Cohort Study.

Katherine L Smulligan, Patrick Carry, Mathew J Wingerson, Catherine Donahue, Julie C Wilson, David R Howell

Abstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katherine L Smulligan
Patrick Carry
Mathew J Wingerson
Catherine Donahue
Julie C Wilson

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Modulating Exercise Dosage to Improve Concussion Rehabilitation: A Randomized Clinical TrialR01HD108133 · NICHD · UNIVERSITY OF COLORADO DENVER · PI David R. Howell · 2022 to 2026
$3.3M
Sex Differences in Brain Structure and Function After Sports-Related ConcussionR01NS100952 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI KOERTE, INGA KATHARINA · 2017 to 2022
$2.9M
Interdisciplinary Training in Musculoskeletal ResearchT32AR080630 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI Karin A Payne, MICHAEL J ZUSCIK · 2022 to 2026
$1.7M
Improving quantitative recovery outcomes from concussion with aerobic exercise trainingR03HD094560 · NICHD · UNIVERSITY OF COLORADO DENVER · PI HOWELL, DAVID R. · 2018 to 2019
$318k
A novel smartphone-based tool to quantify dual-task gait performance for concussion assessmentR43NS108823 · NINDS · CONTROL ONE, LLC · PI LUGADE, VIPUL · 2019 to 2019
$150k
2022 Pediatric Research in Sports Medicine (PRiSM) Annual ConferenceR13AR080451 · NIAMS · UNIVERSITY OF COLORADO DENVER · PI HOWELL, DAVID R. · 2022 to 2024
$45k
NCATS NIH HHS UL1 TR002535NIAMS NIH HHS R13 AR080451NIAMS NIH HHS T32 AR080630NICHD NIH HHS R01 HD108133NICHD NIH HHS R03 HD094560NINDS NIH HHS R01 NS100952NINDS NIH HHS R43 NS108823
6 · The paper itself

Abstract

purposeThis study aimed to examine associations between clinical measures (self-reported and clinician administered) and subsequent injury rates in the year after concussion return to play (RTP) among adolescent athletes.

methodsWe performed a prospective, longitudinal study of adolescents ages 13-18 yr. Each participant was initially assessed within 21 d of concussion and again within 5 d of receiving RTP clearance from their physician. Participants completed self-report measures: the Pittsburgh Sleep Quality Index and Tampa Scale of Kinesiophobia, and clinician-administered measures: single- and dual-task tandem gait and reaction time (RT; simple and clinical) assessments. They then completed monthly surveys for a year after RTP, which assessed exposure to injury (sport participation) and subsequent injuries (musculoskeletal or concussions) sustained. We used Poisson regression models to calculate injury rate ratios with the number of subsequent injuries sustained as the outcome, adjusted for RTP clearance time and competitive exposures for each measure.

resultsForty-one participants were included (age = 15.5 ± 1.3 yr, 56% female, 9.6 ± 4.6 d postconcussion; 38.0 ± 31.5 d to RTP). A higher injury rate per athletic exposure was observed for simple RT ≥ 505 ms versus <505 ms (injury rate ratio = 2.96, 95% confidence interval = 1.41-6.60, P = 0.005). Injury rates did not significantly differ by Pittsburgh Sleep Quality Index or Tampa Scale of Kinesiophobia scores, single/dual-task tandem gait time, or clinical RT.

conclusionsSimple RT may be one risk factor that is associated with higher rates of subsequent injury after adolescent concussion. A simple RT measure incorporated into a comprehensive concussion RTP assessment may identify some individuals at higher risk of subsequent injury in the year after concussion, although further research is needed to better understand this relationship.

Indexed as

Athletic InjuriesBrain ConcussionReturn to SportAdolescentFemaleGaitHumansLongitudinal StudiesMaleProspective StudiesReaction TimeSelf ReportSleep Quality

Identifiers

PMID39733225
PMCPMC11729354

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.