Evidence map›Paper›PMID 39733210›Full record

ArticleScientific reports2024

Self-propelling, protein-bound magnetic nanobots for efficient in vitro drug delivery in triple negative breast cancer cells.

Neha Naikwadi, Milan Paul, Swati Biswas, Sohan Chitlange, Ravindra Wavhale

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Neha NaikwadiDepartment of Pharmaceutical Chemistry, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, India.
Milan PaulNanomedicine Research Laboratory, Department of Pharmacy, Birla Institute of Technology &, Science-Pilani, Hyderabad Campus, Medchal, Hyderabad, 500078, Telangana, India.
Swati BiswasNanomedicine Research Laboratory, Department of Pharmacy, Birla Institute of Technology &, Science-Pilani, Hyderabad Campus, Medchal, Hyderabad, 500078, Telangana, India. swati.biswas@hyderabad.bits-pilani.ac.in.
Sohan ChitlangeDepartment of Pharmaceutical Chemistry, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, India.
Ravindra WavhaleDepartment of Pharmaceutical Chemistry, Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, India. ravindra.wavhale@dypvp.edu.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of self-propelling magnetic nanobots represents a significant advancement in the field of drug delivery. These magneto-nanobots offer precise control over drug targeting and possess the capability to navigate deep into tumor tissues, thereby addressing multiple challenges associated with conventional cancer therapies. Here, Fe-GSH-Protein-Dox, a novel self-propelling magnetic nanobot conjugated with a biocompatible protein surface and loaded with doxorubicin for the treatment of triple-negative breast cancer (TNBC), is reported. The self-propulsion of magnetic nanobots occurs due to a catalytic interaction between Fe

Indexed as

DoxorubicinDrug Delivery SystemsTriple Negative Breast NeoplasmsCell Line, TumorDrug CarriersEndocytosisFemaleHumansHydrogen PeroxideMagnetite NanoparticlesReactive Oxygen SpeciesDoxorubicinDrug CarriersHydrogen PeroxideMagnetite NanoparticlesReactive Oxygen SpeciesDrug delivery systemMagnetic nanobotsSelf-propellingTriple negative breast cancer (TNBC)

Identifiers

PMID39733210
PMCPMC11682353

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.