Evidence map›Paper›PMID 39733201›Full record

ArticleJournal of cardiovascular translational research2025

Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome.

Facai Cui, Xueliang Pei, Mingzhi Ling, Fengxia Guo

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Facai CuiDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, China. cuifacai1985@zzu.edu.cn.ORCID 0009-0005-7858-6456
Xueliang PeiDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, China.
Mingzhi LingDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, China.
Fengxia GuoDepartment of Clinical Laboratory, Henan Provincial People's Hospital, Zhengzhou, China.

Funding

National Natural Science Foundation of China 82002199
6 · The paper itself

Abstract

This study explored the early diagnosis and prognostic value of copeptin in non-ST-segment elevation acute coronary syndrome (NSTE-ACS). 171 patients with chest pain or myocardial ischemia symptoms were enrolled. Patients with NSTE-ACS were further divided into the non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA). All NSTE-ACS patients were followed up to record the occurrence of Major Adverse Cardiovascular Events (MACEs). Serum copeptin concentration in the NSTE-ACS group was significantly higher than that in the control group. The Area under the curve (AUC) value of copeptin in the diagnosis of NSTE-ACS was 0.798. The combined AUC value of copeptin and hypersensitive troponin I (hs-TnI) to NSTE-ACS increased to 0.930. In addition, copeptin and hs-TnI have been proven to be independent risk factors for MACEs in patients with NSTE-ACS. The use of copeptin in combination with conventional myocardial markers contributes to the early diagnosis and short-term prognosis assessment of NSTE-ACS.

Indexed as

Acute Coronary SyndromeAngina, UnstableGlycopeptidesNon-ST Elevated Myocardial InfarctionAgedBiomarkersCase-Control StudiesEarly DiagnosisFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsBiomarkerscopeptinsGlycopeptidesTroponin ICopeptinNegative predictive valueNon-ST-elevation acute coronary syndromePrognosisSensitivity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.