Evidence map›Paper›PMID 39733176›Full record

ArticleAnalytical and bioanalytical chemistry2025

Gold nanoclusters/manganese dioxide nanosheets hybrid nanozyme with fluorescence and oxidase-like activity for dual-mode detection of acetylcholinesterase and inhibitors screening.

Jie Lv, Chengcai He, Jingcheng Cao, Qiuyan Shuai, Xifang Liu, Meng Li, Yulong Lin

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Fluorescence nanozyme B-CDs@SiOAnalytical and bioanalytical chemistry · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie Lv *College of Pharmacy, Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, 050017, China.
Chengcai He *College of Pharmacy, Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, 050017, China.
Jingcheng CaoDepartment of Orthopaedic Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, 050051, China.
Qiuyan ShuaiCollege of Pharmacy, Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, 050017, China.
Xifang LiuNeurology Department, Shijiazhuang People's Hospital, Shijiazhuang, 050000, China.
Meng LiCollege of Pharmacy, Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, 050017, China. limeng@hebmu.edu.cn.
Yulong LinCollege of Pharmacy, Key Laboratory of Innovative Drug Development and Evaluation, Hebei Medical University, Shijiazhuang, 050017, China. yllin@hebmu.edu.cn.

Funding

the Central Guidance on Local Science and Technology Development Fund of Hebei Province 226Z2601Gthe Youth Top-notch Talents Supporting Plan of Hebei Province QNBJ19004
6 · The paper itself

Abstract

The abnormal expression of acetylcholinesterase (AChE) is linked to the development of various diseases. Accurate determination of AChE activity as well as screening AChE inhibitors (AChEIs) holds paramount importance for early diagnosis and treatment of AChE-related diseases. Herein, a fluorescent and colorimetric dual-channel probe based on gold nanoclusters (AuNCs) and manganese dioxide nanosheets (MnO

Indexed as

AcetylcholinesteraseCholinesterase InhibitorsGoldManganese CompoundsMetal NanoparticlesNanostructuresOxidesColorimetryFluorescenceFluorescent DyesHumansLimit of DetectionOxidoreductasesSpectrometry, FluorescenceAcetylcholinesteraseCholinesterase InhibitorsFluorescent DyesGoldManganese Compoundsmanganese dioxideOxidesOxidoreductasesAcetylcholinesteraseDual-channel probeInhibitors screeningNanozyme

Identifiers

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Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.