Evidence map›Paper›PMID 39733047›Full record

SynthesisAesthetic plastic surgery2025

Hyperbaric Oxygen Therapy in Aesthetic Medicine and Anti-Aging: A Systematic Review.

Sean M Fisher, Rami D Sherif, Zachary M Borab, Nishant Ganesh Kumar, Rod J Rohrich

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sean M FisherDallas Plastic Surgery Institute, 9101 N Central Expy, Dallas, Texas, 75225, USA.
Rami D SherifDallas Plastic Surgery Institute, 9101 N Central Expy, Dallas, Texas, 75225, USA. Rami.Sherif@DPSI.org.ORCID 0000-0003-4514-9450
Zachary M BorabDallas Plastic Surgery Institute, 9101 N Central Expy, Dallas, Texas, 75225, USA.
Nishant Ganesh KumarDallas Plastic Surgery Institute, 9101 N Central Expy, Dallas, Texas, 75225, USA.
Rod J RohrichDallas Plastic Surgery Institute, 9101 N Central Expy, Dallas, Texas, 75225, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionContinued interest in the optimization of recovery in aesthetics has led to the exploration of adjunctive therapies. Hyperbaric oxygen therapy (HBOT) serves as one such therapy that may have an impact in this field. HBOT is hypothesized to improve ischemia, reduce swelling, and minimize secondary hypoxic tissue damage. Its application in aesthetic procedures aims to improve healing, reduce downtime, and enhance the overall quality of outcomes.

methodsA systematic review was performed, searching the PubMed database. The protocol was developed following the Preferred Reporting for Items for Systematic Reviews-Protocols (PRISMA) guidelines. Included studies evaluated the use of HBOT in aesthetic surgery, medicine, and longevity and anti-aging. Selected studies matched predetermined criteria according to the employed intervention and outcomes.

resultsThe systematic review was performed in April 2024, with the primary search yielding 591 articles. Abstract review resulted in 53 articles of potential relevance. Comprehensive review of the articles and manual reference checks was performed, independently, by two authors. This yielded a total of 15 articles meeting inclusion criteria.

conclusionsHBOT may serve a valuable adjunct in aesthetic surgery, medicine, and anti-aging. However, the evidence to support its use, and justify its cost, is limited. This review serves as an update, capturing the currently available literature on HBOTs use in aesthetics, and provides the first discussion of HBOTs role in anti-aging. It underscores the need for future large-scale, randomized trials with standardization of HBOT protocols being employed to allow for full assessment of HBOTs utility in this clinical space. LEVEL OF EVIDENCE V: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Cosmetic TechniquesHyperbaric OxygenationSkin AgingSurgery, PlasticEstheticsHumansRejuvenationTreatment OutcomeAesthetic medicineAesthetic surgeryAnti-aging therapyHyperbaric oxygen therapyOutcomes optimizationWound healing

Identifiers

PMID39733047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.